Evidence map›Paper›PMID 21848345›Full record

ReviewChemical reviews2011

Isoprostane generation and function.

Ginger L Milne, Huiyong Yin, Klarissa D Hardy, Sean S Davies, L Jackson Roberts

Abstract readReview
In one paragraph

Review in Chemical reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 164 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
164citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

164 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Exhaled Breath Analysis in Diagnosis of Malignant Pleural Mesothelioma: Systematic Review.International journal of environmental research and public health · 2020
    Pooled it
  3. Trial
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  9. Article
  10. Review
  11. Article
  12. Observational
  13. Article
  14. Review
  15. Article
  16. Article
  17. Rationale for the Use of 8-Aminoguanine for the Management of Cystitis.International journal of urology : official journal of the Japanese Urological Association · 2026
    Review
  18. Article
  19. Review
  20. Article

104 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ginger L MilneDivision of Clinical Pharmacology, Vanderbilt University, Nashville, Tennessee 37232-6602, USA. ginger.milne@vanderbilt.edu
Huiyong Yin
Klarissa D Hardy
Sean S Davies
L Jackson Roberts

Funding

Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI OWEN P MCGUINNESS · 2012 to 2026
$29.3M
TRANSGENIC MOUSE/ ES CELL SHARES RESOURCESP60DK020593 · NIDDK · VANDERBILT UNIVERSITY · PI MCGUINNESS, OWEN P · 1986 to 2011
$28.1M
Structural Biology Facility CoreP30ES000267 · NIEHS · VANDERBILT UNIVERSITY · PI GUENGERICH, F PETER · 1985 to 2014
$20.3M
THE PHARMACOLOGY OF INHIBITORS OF HEME PROTEIN-CATALYZED LIPID PEROXIDATIONP50GM015431 · NIGMS · VANDERBILT UNIVERSITY · PI CAPRIOLI, RICHARD M · 1985 to 2010
$15.0M
Protein Adducts and Proteome Profiles in Oxidative StressP01ES013125 · NIEHS · VANDERBILT UNIVERSITY · PI BROWN, H. ALEX · 2005 to 2012
$12.6M
Therapeutic Modulation of Endothelial Cell TetrahydrobiopterinP01GM015431 · NIGMS · VANDERBILT UNIVERSITY · PI MARNETT, LAWRENCE J. · 2011 to 2015
$9.5M
Formation and Metabolism of 15-deoxy-delta-12, 14-prostaglandin J2 in VivoF31AG035483 · NIA · VANDERBILT UNIVERSITY · PI JACKSON, KLARISSA D · 2009 to 2011
$31k
NIA NIH HHS F31 AG035483NIDDK NIH HHS DK20593NIDDK NIH HHS P30 DK020593NIDDK NIH HHS P60 DK020593NIEHS NIH HHS ES000267NIEHS NIH HHS ES13125NIEHS NIH HHS P01 ES013125NIEHS NIH HHS P30 ES000267NIGMS NIH HHS GM15431NIGMS NIH HHS P01 GM015431NIGMS NIH HHS P50 GM015431
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HumansIsoprostanesLipid PeroxidationOxidative StressReactive Oxygen SpeciesIsoprostanesReactive Oxygen Species

Identifiers

PMID21848345
PMCPMC3192249

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.