ReviewCurrent rheumatology reports2011
Synovial tissue heterogeneity and peripheral blood biomarkers.
Review in Current rheumatology reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- The access route through the anatomical snuffbox in ultrasound-guided synovial biopsy of the wrist allows for a safe and effective collection of tissue samples in inflammatory arthritis.Arthritis research & therapy · 2023Article
- Precision medicine in rheumatoid arthritis.Best practice & research. Clinical rheumatology · 2022Review
- The Genetic, Environmental, and Immunopathological Complexity of Autoantibody-Negative Rheumatoid Arthritis.International journal of molecular sciences · 2021Review
- Significant association between joint ultrasonographic parameters and synovial inflammatory factors in rheumatoid arthritis.Arthritis research & therapy · 2019Article
- Synovial Tissue Heterogeneity in Rheumatoid Arthritis and Changes With Biologic and Targeted Synthetic Therapies to Inform Stratified Therapy.Frontiers in medicine · 2019Review
- Liquid biopsies to guide therapeutic decisions in rheumatoid arthritis.Translational research : the journal of laboratory and clinical medicine · 2018Review
- Targeting the programmed cell death-1 pathway in rheumatoid arthritis.Autoimmunity reviews · 2017Review
- Article
- Increased chemotaxis and activity of circulatory myeloid progenitor cells may contribute to enhanced osteoclastogenesis and bone loss in the C57BL/6 mouse model of collagen-induced arthritis.Clinical and experimental immunology · 2016Article
- Immunopathologic characterization of ultrasound-defined synovitis in rheumatoid arthritis patients in clinical remission.Arthritis research & therapy · 2016Article
- Advances and challenges in hemophilic arthropathy.Seminars in hematology · 2016Review
- The draining lymph node in rheumatoid arthritis: current concepts and research perspectives.BioMed research international · 2015Review
- Association of systemic and intra-articular osteoclastogenic potential, pro-inflammatory mediators and disease activity with the form of inflammatory arthritis.International orthopaedics · 2014Article
- B cells in rheumatoid arthritis: from pathogenic players to disease biomarkers.BioMed research international · 2014Review
- Moving towards personalized medicine in rheumatoid arthritis.Arthritis research & therapy · 2014Article
- Treatment comparison in rheumatoid arthritis: head-to-head trials and innovative study designs.BioMed research international · 2014Review
- The problem of choice: current biologic agents and future prospects in RA.Nature reviews. Rheumatology · 2013Review
- Inflammatory lesions in the bone marrow of rheumatoid arthritis patients: a morphological perspective.Arthritis research & therapy · 2012Review
- Assessment of synovitis to predict bone erosions in rheumatoid arthritis.Therapeutic advances in musculoskeletal disease · 2012Article
- Synovial cytokine expression in psoriatic arthritis and associations with lymphoid neogenesis and clinical features.Arthritis research & therapy · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rheumatoid arthritis is characterized by multiple pathobiological processes and heterogeneous clinical phenotypes. Not surprisingly, the inflamed synovium harbors an equally complex pathology. This includes variability in infiltrating and resident cell populations, spatial arrangements, and cell-cell interactions, as well as gene expression profiles. Remarkable progress in our understanding of the many facets of tissue heterogeneity has been facilitated by the increasing availability of patients' material and the development of advanced research technologies. The next challenge is to capitalize on the large amount of data generated to elucidate the specific pathogenic pathways disparately activated in different patients and/or different phases of the disease. When tissue pathology can be reliably explored through noninvasive circulating biomarkers, then the circle will be closed. We attempt to highlight key advances in the understanding of synovial tissue heterogeneity in rheumatoid arthritis and summarize novel perspectives in synovial biomarker discovery in relation to peripheral blood.
Indexed as
Identifiers
21847543What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.