ArticleInternational journal of clinical oncology2012
Leptomeningeal carcinomatosis associated with gastric cancer.
Article in International journal of clinical oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Radiotherapy in Leptomeningeal Disease: A Systematic Review of Randomized and Non-randomized Trials.Frontiers in oncology · 2019Pooled it
- Clinical outcome and molecular characterization of brain metastases from esophageal and gastric cancer: a systematic review.Medical oncology (Northwood, London, England) · 2017Pooled it
- Leptomeningeal Metastasis from Gastric Signet Ring Cell Carcinoma: A Case Report and Literature Review.Journal of gastrointestinal cancer · 2026Review
- Leptomeningeal carcinomatosis in gastric cancer: a single-center retrospective analysis of 86 cases.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026Article
- Autopsy diagnosis of leptomeningeal carcinomatosis, the first manifestation of gastric adenocarcinoma: a rare case report and review of the literature.Gastroenterology and hepatology from bed to bench · 2021Article
- A case of leptomeningeal carcinomatosis in advanced gastric adenocarcinoma with controlled peritoneal dissemination.International cancer conference journal · 2019Article
- Exclusive Cerebellar and Leptomeningeal Metastases from Early Gastric Cancer 14 Months after Proximal Gastrectomy: An Autopsy Case Report.NMC case report journal · 2019Article
- Leptomeningeal carcinomatosis of gastric cancer misdiagnosed as vestibular schwannoma.Journal of Korean Neurosurgical Society · 2014Article
- Leptomeningeal carcinomatosis from gastric cancer: single institute retrospective analysis of 9 cases.Annals of surgical treatment and research · 2014Article
- Neuro-ophthalmologic complications of neoplastic leptomeningeal disease.Current neurology and neuroscience reports · 2013Review
- A case of metastatic leptomeningeal carcinomatosis from early gastric carcinoma.World journal of surgical oncology · 2012Article
- Malignant transformation and subsequent leptomeningeal carcinomatosis of a gastric polyp in a dog.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLeptomeningeal carcinomatosis (LMC) is a rare but devastating complication of gastric cancer.
methodsThe subjects were 12 gastric cancer patients who were diagnosed as having LMC at the Shizuoka Cancer Center between October 2002 and March 2009. We conducted a retrospective survey of the medical records of the study subjects and collected data on the clinical features, treatment modalities employed/outcomes, and survival of the patients.
resultsOf the 12 patients, 9 (75%) were male, and the median age was 63 years. Histopathologically, the majority of the patients (83%) had diffuse-type adenocarcinoma. At the time of diagnosis of the LMC, the other major sites of metastasis were the peritoneum (75%) and lymph nodes (50%). The median duration from the diagnosis of gastric cancer to the diagnosis of LMC was 15.6 months. While the treatment strategy changed with time, intrathecal chemotherapy (n = 10), followed by whole brain irradiation (n = 7) and subsequent ventriculo-peritoneal shunt (n = 3) was performed in 10 of the patients. Improvement of neurological functions was observed in 6 of the 10 patients. The median overall survival time from the diagnosis of LMC in all the 12 patients was 60 days. One patient survived for a considerably long period of 532 days.
conclusionsMultidisciplinary treatment, including ventriculo-peritoneal shunt for LMC secondary to gastric cancer, may benefit selected patients, but further accumulation of clinical cases is necessary.
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