SynthesisTrials2011
A meta-review of evidence on heart failure disease management programs: the challenges of describing and synthesizing evidence on complex interventions.
Synthesis in Trials, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Does multidisciplinary disease management program lower hospitalization and mortality among patients with heart failure? A systematic review and meta-analysis of randomized controlled trials.BMC health services research · 2026Pooled it
- Impact of primary care involvement and setting on multidisciplinary heart failure management: a systematic review and meta-analysis.ESC heart failure · 2021Pooled it
- Pooled it
- Facilitators and barriers to quality of care in maternal, newborn and child health: a global situational analysis through metareview.BMJ open · 2014Pooled it
- How and Why Telehealth Interventions Improve Self-Care Among Vulnerable Groups of Patients With Heart Failure: Scoping Review and Rapid Realist Synthesis.JMIR human factors · 2026Article
- Validation of Psychometric Properties of Partners in Health Scale for Heart Failure.Journal of clinical medicine · 2024Article
- Identifying daily activities of patient work for type 2 diabetes and co-morbidities: a deep learning and wearable camera approach.Journal of the American Medical Informatics Association : JAMIA · 2022Article
- Database combinations to retrieve systematic reviews in overviews of reviews: a methodological study.BMC medical research methodology · 2020Article
- Effectiveness of telemedicine systems for adults with heart failure: a meta-analysis of randomized controlled trials.Heart failure reviews · 2020Review
- Patient Commitment to Health (PACT-Health) in the Heart Failure Population: A Focus Group Study of an Active Communication Framework for Patient-Centered Health Behavior Change.Journal of medical Internet research · 2019Article
- Article
- Usefulness of Wearable Cameras as a Tool to Enhance Chronic Disease Self-Management: Scoping Review.JMIR mHealth and uHealth · 2019Article
- A physician targeted intervention improves prescribing in chronic heart failure in general medical units.BMC health services research · 2018Article
- Improving kNowledge Transfer to Efficaciously RAise the level of Contemporary Treatment in Heart Failure (INTERACT-in-HF): Study protocol of a mixed methods study.International journal of care coordination · 2017Article
- Design of a multicentre randomized controlled trial to assess the safety and efficacy of dose titration by specialized nurses in patients with heart failure. ETIFIC study protocol.ESC heart failure · 2017Review
- Can home care for homebound patients with chronic heart failure reduce hospitalizations and costs?PloS one · 2017Article
- A qualitative analysis to optimize a telemonitoring intervention for heart failure patients from disparity communities.BMC medical informatics and decision making · 2016Article
- Establishing a pragmatic framework to optimise health outcomes in heart failure and multimorbidity (ARISE-HF): A multidisciplinary position statement.International journal of cardiology · 2016Review
- Heart failure patients' descriptions of participation in structured home care.Health expectations : an international journal of public participation in health care and health policy · 2015Article
- [Chronic heart failure : current guideline recommendations and innovations].Der Internist · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
backgroundDespite favourable results from past meta-analyses, some recent large trials have not found heart failure (HF) disease management programs to be beneficial. To explore reasons for this, we evaluated evidence from existing meta-analyses.
methodsSystematic review incorporating meta-review was used. We selected meta-analyses of randomized controlled trials published after 1995 in English that examined the effects of HF disease management programs on key outcomes. Databases searched: MEDLINE, EMBASE, Cochrane Database of Systematic Reviews (CDSR), DARE, NHS EED, NHS HTA, Ageline, AMED, Scopus, Web of Science and CINAHL; cited references, experts and existing reviews were also searched.
results15 meta-analyses were identified containing a mean of 18.5 randomized trials of HF interventions +/- 10.1 (range: 6 to 36). Overall quality of the meta-analyses was very mixed (Mean AMSTAR Score = 6.4 +/- 1.9; range 2-9). Reporting inadequacies were widespread around populations, intervention components, settings and characteristics, comparison, and comparator groups. Heterogeneity (statistical, clinical, and methodological) was not taken into account sufficiently when drawing conclusions from pooled analyses.
conclusionsMeta-analyses of heart failure disease management programs have promising findings but often fail to report key characteristics of populations, interventions, and comparisons. Existing reviews are of mixed quality and do not adequately take account of program complexity and heterogeneity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.