Evidence map›Paper›PMID 21845374›Full record

ReviewJournal of gastrointestinal cancer2012

Pancreatic involvement by plasma cell neoplasms.

Rodrigo Lopes da Silva

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Journal of gastrointestinal cancer, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Unusual origin of a pancreatic head mass.Przeglad gastroenterologiczny · 2026
    Article
  3. Article
  4. A Rare Cause Mimicking Pancreatic Cancer: Extramedullary Plasmacytoma.Journal of clinical practice and research · 2024
    Article
  5. Article
  6. Article
  7. Multiple myeloma presenting as plasmacytoma causing obstructive jaundice.Proceedings (Baylor University. Medical Center) · 2020
    Article
  8. Review
  9. Pancreatic Extramedullary Plasmacytoma Presenting as a Pancreatic Mass.Clinical medicine insights. Gastroenterology · 2018
    Article
  10. Article
  11. Rare pancreas tumor mimicking adenocarcinoma: Extramedullary plasmacytoma.World journal of gastrointestinal endoscopy · 2014
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Rodrigo Lopes da SilvaHospital Santo António dos Capuchos-CHLC, Alameda Santo António dos Capuchos, 1169-050, Lisbon, Portugal. ronolosi@gmail.com
Hospital Santo António dos Capuchos · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPancreatic involvement by plasma cell neoplasms is an extremely rare event, with only 50 cases described in the literature. They can present as a primary solitary extramedullary plasmacytoma or plasmacytoma secondary to a plasma cell myeloma. Clinical manifestations are due to the presence of a pancreatic mass usually in the pancreas head, which causes extra-biliary obstruction and abdominal pain.

methodsAbdominal imaging including CT scan or endoscopic ultrasound with fine-needle aspiration tissue sampling is essential for the initial diagnostic procedure. However, immunohistochemical analysis of the biopsy specimen or flow cytometry of the aspirated material is crucial to prove the monoclonality and the final diagnosis of a plasma cell neoplasm. DISCUSSION: Management of these situations include radiotherapy, chemotherapy, surgery or combined therapy. Novel medications including the immunomodulatory drugs or the proteasome inhibitors followed by consolidation with intensive chemotherapy and haematopoietic stem cell transplantation are nowadays used as upfront treatment in the cases associated to a plasma cell myeloma.

conclusionDespite the rarity, plasma cell neoplasms should be considered in the differential diagnosis of obstructive jaundice and pancreatic neoplasms since they are potentially treatable situations.

Indexed as

Diagnosis, DifferentialHumansNeoplasms, Plasma CellPancreatic Neoplasms

Identifiers

PMID21845374
OpenAlexW2049133641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.