Evidence map›Paper›PMID 21844880›Full record

ReviewNature reviews. Microbiology2011

Growth of Candida albicans hyphae.

Peter E Sudbery

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 582 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
582citing papers in PubMed, 1 pooled it
25.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

582 citing papers in PubMed, 1 synthesis or guideline pooled it, 1,080 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. mBio · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Ras1-Independent High Iron-Mediated Hyphal Formation inJournal of fungi (Basel, Switzerland) · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Antifungal Activity ofInternational journal of molecular sciences · 2026
    Article
  16. Hijacking competitor-derived signals: RcsB/C drivesApplied and environmental microbiology · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Article

522 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Peter E SudberyDepartment of Molecular Biology and Biotechnology, Sheffield University, Western Bank, Sheffield, UK. P.Sudbery@shef.ac.uk
University of Sheffield · GB

Funding

Biotechnology and Biological Sciences Research Council BB‑F007892
6 · The paper itself

Abstract

The fungus Candida albicans is often a benign member of the mucosal flora; however, it commonly causes mucosal disease with substantial morbidity and in vulnerable patients it causes life-threatening bloodstream infections. A striking feature of its biology is its ability to grow in yeast, pseudohyphal and hyphal forms. The hyphal form has an important role in causing disease by invading epithelial cells and causing tissue damage. This Review describes our current understanding of the network of signal transduction pathways that monitors environmental cues to activate a programme of hypha-specific gene transcription, and the molecular processes that drive the highly polarized growth of hyphae.

Indexed as

Candida albicansCandidiasisEpitheliumFungal ProteinsGene Expression Regulation, FungalHumansHyphaeSignal TransductionTranscription, GeneticFungal Proteins

Identifiers

PMID21844880
OpenAlexW1997437177

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.