Evidence map›Paper›PMID 21844738›Full record

ArticleSexually transmitted diseases2011

Trichomonas vaginalis infection in women who submit self-obtained vaginal samples after internet recruitment.

Charlotte A Gaydos, Yu-Hsiang Hsieh, Mathilda Barnes, Nicole Quinn, Patricia Agreda, Mary Jett-Goheen, Pamela Whittle, Terry Hogan

Abstract read
In one paragraph

Article in Sexually transmitted diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Prevalence and Correlates of Trichomonas vaginalis Infection Among Men and Women in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. A Review of Evidence-Based Care of Symptomatic Trichomoniasis and Asymptomatic Trichomonas vaginalis Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Neglected parasitic infections in the United States: trichomoniasis.The American journal of tropical medicine and hygiene · 2014
    Article
  14. Article
  15. Article
  16. Modern diagnosis of Trichomonas vaginalis infection.Sexually transmitted infections · 2013
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Charlotte A GaydosDepartment of Medicine, Division of Infectious Diseases, Johns Hopkins University, Baltimore, MD, USA. cgaydos@jhmi.edu
Yu-Hsiang Hsieh
Mathilda Barnes
Nicole Quinn
Patricia Agreda
Mary Jett-Goheen
Pamela Whittle
Terry Hogan
Johns Hopkins Medicine · USBaltimore City Health Department · USJohns Hopkins University · USOffice of Infectious Diseases · US

Funding

LC: HIV Prevention Trials Network - Laboratory Support for the SARS-CoV-2 Seroprevalence Study (CoVPN 5002)UM1AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SUSAN H ESHLEMAN, Mark A Marzinke · 2011 to 2026
$100.2M
TrainingU54EB007958 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI Yukari C Manabe · 2007 to 2026
$34.6M
HIV Prevention Trials Network: Network LaboratoryU01AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI ESHLEMAN, SUSAN H · 2006 to 2010
$16.5M
Rapid Multipathogen Detection for POCT and National Diaster ReadinessU54EB007959 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KOST, GERALD JOSEPH · 2007 to 2011
$8.5M
Research Infrastructure for the Hopkins Population CenterR24HD042854 · NICHD · JOHNS HOPKINS UNIVERSITY · PI CHERLIN, ANDREW J · 2003 to 2017
$5.1M
NIAID NIH HHS U01 AI068613NIBIB NIH HHS U54 EB007958NIBIB NIH HHS U54 EB007959NIBIB NIH HHS U54EB007959NICHD NIH HHS R24 HD042854
6 · The paper itself

Abstract

backgroundSubmission of self-obtained vaginal samples (SOVs) collected at home could remove barriers that women face in getting tested for sexually transmitted infections (STIs). Internet recruitment of SOVs is highly acceptable.

methodsSexually active women ≥14 years were recruited by an educational Internet program, available at: www.iwantthekit.org (IWTK), which offered free testing for trichomonas as part of a panel, which also offered testing for chlamydia and gonorrhea. Kits were ordered online, SOVs were sent through US mail to the laboratory, and tested by nucleic acid amplification tests. Demographics and sexual risk factors were accessed by questionnaires. Women called or were contacted to receive their results.

resultsOf women requesting kits, 1525 (43%) returned swabs by mail. In all, 61% were <25 years, 52% were black, and 80% were single. Vaginal discharge was reported by 44%, prevalence for trichomonas was 10% (10% for chlamydia, 1% for gonorrhea), and 18% had at least one prevalent STI. Multivariate logistic regression demonstrated several significantly associated risks factors as follows: adjusted odds ratio for black race was 2.69; for residence of Illinois, 3.85; for not having health insurance, 1.57; for lack of a bachelor's degree, 5.53; for having 2 to 15 partners, 1.60; for having ≥16 partners in previous year, 3.51; for being bisexual, 2.0; for not always using condoms, 3.04; and for having a partner who had a previous STI, 1.71. Age was not associated with trichomonas infection. All infected women were treated.

conclusionsA high prevalence of trichomonas and high sexual risk factors were demonstrated. Internet recruitment was a useful method of screening women for trichomonas infection.

Indexed as

InternetAdolescentAdultCost-Benefit AnalysisDNA, BacterialFemaleHumansMass ScreeningPredictive Value of TestsPrevalenceRisk FactorsSurveys and QuestionnairesTrichomonas vaginalisTrichomonas VaginitisVaginal SmearsYoung AdultDNA, Bacterial

Identifiers

PMID21844738
PMCPMC3157012
OpenAlexW1996446739

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.