ArticleJournal of magnetic resonance (San Diego, Calif. : 1997)2011
Relaxation times and line widths of isotopically-substituted nitroxides in aqueous solution at X-band.
Article in Journal of magnetic resonance (San Diego, Calif. : 1997), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- Axially Chiral Bifluorenylidene Radical Anions with Long Spin-Lattice Relaxation Times at Room Temperature in Fluid Solution.Journal of the American Chemical Society · 2026Article
- Imaging cell phone radiation in tissue mimics with hyperpolarized low-field MRI.Science advances · 2026Article
- What Is the Information Content of EPR Oximetry?Advances in experimental medicine and biology · 2026Review
- Compact 1 GHz electron paramagnetic resonance spectrometer and imager.The Review of scientific instruments · 2025Article
- Have We Been Teaching Continuous Wave EPR Correctly?Journal of chemical education · 2025Article
- Compact Electron Paramagnetic Resonance on a Chip Spectrometer Using a Single Sided Permanent Magnet.ACS sensors · 2024Article
- Stable organic radical qubits and their applications in quantum information science.Innovation (Cambridge (Mass.)) · 2024Review
- Toward a Nanoencapsulated EPR Imaging Agent for Clinical Use.Molecular imaging and biology · 2024Article
- Quantum Mimicry With Inorganic Chemistry.Comments on modern chemistry. Part A, Comments on inorganic chemistry : a journal of critical discussion of the current literature · 2024Article
- Impact of Chlorine Substitution on Electron Spin Relaxation of a Trityl Radical.Applied magnetic resonance · 2022Article
- A Review of Low-Frequency EPR Technology for the Measurement of Brain pO2 and Oxidative Stress.Applied magnetic resonance · 2021Article
- Ligand control of low-frequency electron paramagnetic resonance linewidth in Cr(III) complexes.Dalton transactions (Cambridge, England : 2003) · 2021Article
- Biological validation of electron paramagnetic resonance (EPR) image oxygen thresholds in tissue.The Journal of physiology · 2021Review
- Article
- Azaadamantyl nitroxide spin label: complexation with β-cyclodextrin and electron spin relaxation.Free radical research · 2018Article
- Synthesis and Electron Spin Relaxation of Tetracarboxylate Pyrroline Nitroxides.The Journal of organic chemistry · 2017Article
- Designing Molecular Probes To Prolong Intracellular Retention: Application to Nitroxide Spin Probes.Bioconjugate chemistry · 2016Article
- Enhancement of Paramagnetic Relaxation by Photoexcited Gold Nanorods.Scientific reports · 2016Article
- In Vivo pO2 Imaging of Tumors: Oxymetry with Very Low-Frequency Electron Paramagnetic Resonance.Methods in enzymology · 2015Review
- Multifrequency Pulsed EPR and the Characterization of Molecular Dynamics.Methods in enzymology · 2015Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Optimization of nitroxides as probes for EPR imaging requires detailed understanding of spectral properties. Spin lattice relaxation times, spin packet line widths, nuclear hyperfine splitting, and overall lineshapes were characterized for six low molecular weight nitroxides in dilute deoxygenated aqueous solution at X-band. The nitroxides included 6-member, unsaturated 5-member, or saturated 5-member rings, most of which were isotopically labeled. The spectra are near the fast tumbling limit with T(1)∼T(2) in the range of 0.50-1.1 μs at ambient temperature. Both spin-lattice relaxation T(1) and spin-spin relaxation T(2) are longer for (15)N- than for (14)N-nitroxides. The dominant contributions to T(1) are modulation of nitrogen hyperfine anisotropy and spin rotation. Dependence of T(1) on nitrogen nuclear spin state m(I) was observed for both (14)N and (15)N. Unresolved hydrogen/deuterium hyperfine couplings dominate overall line widths. Lineshapes were simulated by including all nuclear hyperfine couplings and spin packet line widths that agreed with values obtained by electron spin echo. Line widths and relaxation times are predicted to be about the same at 250 MHz as at X-band.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.