ArticleCell host & microbe2011
Alphavirus entry: NRAMP leads the way.
Article in Cell host & microbe, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Review
- Crossing the Iron Gate: Why and How Transferrin Receptors Mediate Viral Entry.Annual review of nutrition · 2018Review
- Possible role of a cell surface carbohydrate in evolution of resistance to viral infections in old world primates.Journal of virology · 2013Article
- Rift Valley fever virus strain MP-12 enters mammalian host cells via caveola-mediated endocytosis.Journal of virology · 2012Article
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
Abstract
The identity of the receptors that mediate alphavirus entry into host cells has been elusive. In this issue of Cell Host & Microbe, Rose et al. (2011) use a Drosophila RNAi screen to identify NRAMP, an iron transporter with 12 transmembrane domains, as a receptor for Sindbis virus in both insect and mammalian cells.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.