Evidence map›Paper›PMID 21842581›Full record

ArticleUltrasonic imaging2011

Noninvasive assessment of wall-shear rate and vascular elasticity using combined ARFI/SWEI/spectral Doppler imaging system.

Douglas M Dumont, Joshua R Doherty, Gregg E Trahey

Abstract read
In one paragraph

Article in Ultrasonic imaging, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Delineation of Human Carotid Plaque Features In Vivo by Exploiting Displacement Variance.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2019
    Observational
  4. Article
  5. On the Feasibility of Quantifying Fibrous Cap Thickness With Acoustic Radiation Force Impulse (ARFI) Ultrasound.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2016
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Office-based elastographic technique for quantifying mechanical properties of skeletal muscle.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Douglas M DumontDepartment of Biomedical Engineering, Duke University, Durham, NC 27708, USA. dmd@duke.edu
Joshua R Doherty
Gregg E Trahey
Duke University · US

Funding

Training in Medical ImagingT32EB001040 · NIBIB · DUKE UNIVERSITY · PI NIGHTINGALE, KATHRYN RADABAUGH · 2003 to 2018
$4.4M
Acoustic Radiation Force Imaging of ArteriesR01HL075485 · NHLBI · DUKE UNIVERSITY · PI TRAHEY, GREGG E. · 2004 to 2012
$3.2M
NHLBI NIH HHS R01 HL075485NHLBI NIH HHS R01HL075485NIBIB NIH HHS 5T32EB001040NIBIB NIH HHS T32 EB001040
6 · The paper itself

Abstract

The progression of atherosclerotic disease is a complex process believed to be a function of the localized mechanical properties and hemodynamic loading associated with the arterial wall. It is hypothesized that measurements of cardiovascular stiffness and wall-shear rate (WSR) may provide important information regarding vascular remodeling, endothelial function and the growth of soft lipid-filled plaques that could help a clinician better predict the occurrence of clinical events such as stroke. Two novel ARFI based imaging techniques, combined on-axis/off-axis ARFI/Spectral Doppler Imaging (SAD-SWEI) and Gated 2D ARFI/Spectral Doppler Imaging (SAD-Gated), were developed to form co-registered depictions of B-mode echogenicity, ARFI displacements, ARF-excited transverse wave velocity estimates and estimates ofwall-shear rate throughout the cardiac cycle. Implemented on a commercial ultrasound scanner, the developed techniques were evaluated in tissue-mimicking and steady-state flow phantoms and compared with conventional techniques, other published study results and theoretical values. Initial in vivo feasibility of the method is demonstrated with results obtained from scanning the carotid arteries of five healthy volunteers. Cyclic variations over the cardiac cycle were observed in on-axis displacements, off-axis transverse-wave velocities and wall-shear rates.

Indexed as

AdultAnalysis of VarianceAtherosclerosisBlood Flow VelocityCarotid Artery, CommonElasticityElasticity Imaging TechniquesFemaleHemorheologyHumansImage Processing, Computer-AssistedMaleMiddle AgedPhantoms, ImagingPulsatile FlowShear Strength

Identifiers

PMID21842581
PMCPMC3266666
OpenAlexW2043541347

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.