Evidence map›Paper›PMID 21842427›Full record

ArticleDiabetologia2011

The role of continuous subcutaneous insulin infusion therapy in patients with diabetic gastroparesis.

D Sharma, G Morrison, F Joseph, T S Purewal, P J Weston

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Diabetologia, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Optimal prandial timing of bolus insulin in diabetes management: a review.Diabetic medicine : a journal of the British Diabetic Association · 2018
    Pooled it
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Diabetic Gastroparesis and Glycaemic Control.Current diabetes reports · 2019
    Review
  11. Diabetic Gastroparesis.Endocrine reviews · 2019
    Review
  12. Review
  13. Diabetic Gastroparesis: Principles and Current Trends in Management.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2018
    Review
  14. Article
  15. Diabetes and the Stomach.Current treatment options in gastroenterology · 2017
    Review
  16. Glucose variability, HbA1c and microvascular complications.Reviews in endocrine & metabolic disorders · 2016
    Review
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

D SharmaThe Royal Liverpool University Hospital, Prescot Street, Liverpool, L7 8XP, UK. dushyant.sharma@rlbuht.nhs.uk
G Morrison
F Joseph
T S Purewal
P J Weston
University of Liverpool · GBRoyal Liverpool University Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIMS/

objectiveTo describe the effectiveness of continuous subcutaneous insulin infusion (CSII) in patients with symptomatic diabetic gastroparesis and unstable glycaemic control.

methodsData from 26 patients with symptomatic diabetic gastroparesis and unstable glycaemic control using multiple-dose insulin (MDI) regimens, and subsequently managed with CSII, were analysed.

resultsFollowing initiation of CSII, the median length of inpatient bed days associated with hospital admissions related to gastroparesis and glycaemic instability was reduced from 8.5 (range 0-144) days patient( -1) year( -1) prior to CSII to 0 (range 0-15) days patient( -1) year( -1). The median HbA(1c) reduction with CSII was 1.8% (22 mmol/mol; p < 0.05). The median capillary blood glucose (CBG) with CSII was significantly lower than with MDI: 7.7 mmol/l (range 3.8-15.4 mmol/l) vs 9.8 mmol/l (range 2.3-27 mmol/l), respectively, p < 0.001. Glycaemic variability with CSII was significantly reduced compared with MDI: CBG CV 0.37 vs CV 0.53, respectively, p < 0.001. CONCLUSIONS/

interpretationCSII therapy in patients with diabetic gastroparesis results in significant improvement in glycaemic control and reductions in glycaemic variability and number of hospital inpatient bed days.

Indexed as

Insulin Infusion SystemsAdultBody Mass IndexCohort StudiesDiabetes Mellitus, Type 1FemaleFollow-Up StudiesGastrointestinal AgentsGastroparesisGlycated HemoglobinHospitalizationHumansHyperglycemiaHypoglycemiaHypoglycemic AgentsInfusions, SubcutaneousGastrointestinal AgentsGlycated Hemoglobinhemoglobin A1c protein, humanHypoglycemic AgentsInsulin

Identifiers

PMID21842427
OpenAlexW2168766065

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.