Evidence map›Paper›PMID 21841159›Full record

SynthesisBlood2011

EORTC, ISCL, and USCLC consensus recommendations for the treatment of primary cutaneous CD30-positive lymphoproliferative disorders: lymphomatoid papulosis and primary cutaneous anaplastic large-cell lymphoma.

Werner Kempf, Katrin Pfaltz, Maarten H Vermeer, Antonio Cozzio, Pablo L Ortiz-Romero, Martine Bagot, Elise Olsen, Youn H Kim, Reinhard Dummer, Nicola Pimpinelli and 16 more

Abstract readSystematic ReviewConsensus Statement
In one paragraph

Synthesis in Blood, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Results of a Phase II Trial of Brentuximab Vedotin for CD30+ Cutaneous T-Cell Lymphoma and Lymphomatoid Papulosis.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2015
    Trial
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
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  18. Review
  19. Retrospective Evaluation of Clinical and Follow-Up Outcomes in Primary Cutaneous CD30Turkish journal of haematology : official journal of Turkish Society of Haematology · 2025
    Article
  20. Review

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Werner KempfDepartment of Dermatology, University Hospital Zürich, Zürich, Switzerland. werner.kempf@access.uzh.ch
Katrin Pfaltz
Maarten H Vermeer
Antonio Cozzio
Pablo L Ortiz-Romero
Martine Bagot
Elise Olsen
Youn H Kim
Reinhard Dummer
Nicola Pimpinelli
Sean Whittaker
Emmilia Hodak
Lorenzo Cerroni
Emilio Berti
Steve Horwitz
H Miles Prince
Joan Guitart
Teresa Estrach
José A Sanches
Madeleine Duvic
Annamari Ranki
Brigitte Dreno
Sonja Ostheeren-Michaelis
Robert Knobler
Gary Wood
Rein Willemze

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary cutaneous CD30(+) lymphoproliferative disorders (CD30(+) LPDs) are the second most common form of cutaneous T-cell lymphomas and include lymphomatoid papulosis and primary cutaneous anaplastic large-cell lymphoma. Despite the anaplastic cytomorphology of tumor cells that suggest an aggressive course, CD30(+) LPDs are characterized by an excellent prognosis. Although a broad spectrum of therapeutic strategies has been reported, these have been limited mostly to small retrospective cohort series or case reports, and only very few prospective controlled or multicenter studies have been performed, which results in a low level of evidence for most therapies. The response rates to treatment, recurrence rates, and outcome have not been analyzed in a systematic review. Moreover, international guidelines for staging and treatment of CD30(+) LPDs have not yet been presented. Based on a literature analysis and discussions, recommendations were elaborated by a multidisciplinary expert panel of the Cutaneous Lymphoma Task Force of the European Organization for Research and Treatment of Cancer, the International Society for Cutaneous Lymphomas, and the United States Cutaneous Lymphoma Consortium. The recommendations represent the state-of-the-art management of CD30(+) LPDs and include definitions for clinical endpoints as well as response criteria for future clinical trials in CD30(+) LPDs.

Indexed as

Case-Control StudiesCohort StudiesEuropean UnionHumansKi-1 AntigenLymphoma, Primary Cutaneous Anaplastic Large CellLymphomatoid PapulosisPractice Guidelines as TopicPrognosisSocieties, MedicalUnited StatesKi-1 Antigen

Identifiers

PMID21841159
PMCPMC3204726

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.