Evidence map›Paper›PMID 21841158›Full record

ArticleAmerican journal of epidemiology2011

Hypertension status, treatment, and control among spousal pairs in a middle-aged adult cohort.

Mara McAdams DeMarco, Josef Coresh, Mark Woodward, Kenneth R Butler, W H Linda Kao, Thomas H Mosley, Michelle Hindin, Cheryl A M Anderson

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in American journal of epidemiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Spousal concordance for hypertension: A meta-analysis of observational studies.Journal of clinical hypertension (Greenwich, Conn.) · 2017
    Pooled it
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  7. Alcohol Use and Blood Pressure Among Older Couples: The Moderating Role of Negative Marital Quality.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mara McAdams DeMarcoDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA. mmcadams@jhsph.edu
Josef Coresh
Mark Woodward
Kenneth R Butler
W H Linda Kao
Thomas H Mosley
Michelle Hindin
Cheryl A M Anderson
Johns Hopkins University · US

Funding

CARDIOVASCULAR EPIDEMIOLOGY INSTITUTIONAL TRAININGT32HL007024 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Elizabeth Selvin · 1985 to 2026
$17.5M
COMMUNITY AND COHORT SURVEILLANCE PROGRAMS-N01HC55015N01HC055015 · HC · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI CHAMBLESS, LLOYD E · 1985 to 2006
$1.1M
COMMUNITY AND COHORT SURVEILLANCE PROGRAMN01HC055016 · HC · BAYLOR COLLEGE OF MEDICINE · PI BALLANTYNE, CHRISTIE M · 1985 to 2000
$785k
FIELD CENTER FOR CCSPN01HC055019 · HC · UNIVERSITY OF MINNESOTA TWIN CITIES · PI FOLSOM, AARON R · 1985 to 2000
$748k
FIELD CENTERN01HC055021 · HC · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI JONES, DANIEL W · 1985 to 2000
$617k
CCSP-FIELD CENTERN01HC055020 · HC · JOHNS HOPKINS UNIVERSITY · PI NIETO, F JAVIER · 1985 to 2000
$334k
CENTRAL HEMOSTATIS LABORATORY FOR CCSPN01HC055022 · HC · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WU, KENNETH K · 1985 to 2000
$264k
CCSP--FIELD CENTER AND ULTRASOUND READING CENTERN01HC055018 · HC · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI HEISS, GERARDO · 1985 to 2000
$104k
SKELETAL MUSCLE ENERGY CONVERTOR FOR CARDIAC ASSISTANCER41HL055018 · NHLBI · THORATEC LABORATORIES CORPORATION · PI FARRAR, DAVID J · 1995 to 1995
–
RAPID IMMUNODETECTION OF CARDIAC PROTEINS IN WHOLE BLOODR41HL055019 · NHLBI · SELECTIVE TECHNOLOGIES, INC. · PI MARTIN, GLENN B · 1995 to 1995
–
SKELETAL MUSCLE ENGERGY CONVERTOR FOR CARDIAC ASSISTANCER42HL055018 · NHLBI · THORATEC LABORATORIES CORPORATION · PI FARRAR, DAVID J · 1998 to 1999
–
NHLBI NIH HHS 5T32HL007024NHLBI NIH HHS N01 HC055015NHLBI NIH HHS N01 HC055016NHLBI NIH HHS N01 HC055018NHLBI NIH HHS N01 HC055019NHLBI NIH HHS N01 HC055020NHLBI NIH HHS N01 HC055021NHLBI NIH HHS N01 HC055022NHLBI NIH HHS N01-HC-55015NHLBI NIH HHS N01-HC-55016NHLBI NIH HHS N01-HC-55018NHLBI NIH HHS N01-HC-55019NHLBI NIH HHS N01-HC-55020NHLBI NIH HHS N01-HC-55021NHLBI NIH HHS N01-HC-55022NHLBI NIH HHS T32 HL007024
6 · The paper itself

Abstract

Hypertension status among spouses is known to be concordant, but previous studies relied on history rather than direct measurement, and few data exist on treatment and control between spouses. The goal of this study was to estimate the spousal association of hypertension status, treatment, and control in adults. The authors identified and analyzed data on 4,500 pairs from the Atherosclerosis Risk in Communities (ARIC) cohort, which sampled middle-aged adults and their spouses in 1986-1989, with 3 follow-up visits 3 years apart. Generalized estimating equations were used in logistic regression analyses to calculate the odds ratio of a spouse's being hypertensive on the basis of the other spouse's hypertension status across 4 visits, adjusting for age, race, body mass index, smoking status, and sodium intake in both individuals. There are marginally increased odds of hypertension for spouses married to someone with hypertension (odds ratio (OR) = 1.15, 95% confidence interval (CI): 1.06, 1.25). Treatment was positively associated between spouses (OR = 1.35, 95% CI: 1.10, 1.67). Control was suggestive of an association, although it was not statistically significant (OR = 1.21, 95% CI: 0.93, 1.56). In middle-aged adults, hypertension status and treatment were moderately associated between spouses after controlling for shared environment. Physicians may target hypertension education and prevention to spouses as a pair rather than as 2 separate patients.

Indexed as

AdultAgedAntihypertensive AgentsBlood PressureCohort StudiesFollow-Up StudiesHumansHypertensionLogistic ModelsMarriageMiddle AgedRisk FactorsSpousesUnited StatesAntihypertensive Agents

Identifiers

PMID21841158
PMCPMC3203378
OpenAlexW2134071597

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.