Evidence map›Paper›PMID 21839011›Full record

ArticleBlood transfusion = Trasfusione del sangue2011

Seroprevalence of human immunodeficiency virus, hepatitis B and C viruses and syphilis among blood donors in Koudougou (Burkina Faso) in 2009.

Marius Bolni Nagalo, Mahamoudou Sanou, Cyrille Bisseye, Marilène Inès Kaboré, Yacouba K Nebie, Kisito Kienou, Alice Kiba, Honorine Dahourou, Siaka Ouattara, Jean Didier Zongo and 1 more

Abstract read
In one paragraph

Article in Blood transfusion = Trasfusione del sangue, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 6 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 6 syntheses or guidelines pooled it, 99 citations in OpenAlex.

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  11. A case-control study of risk factors for incident hepatitis B virus infection in South African blood donors.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2024
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  18. Magnitude and trend of HIV andAfrican health sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Marius Bolni NagaloNational Blood Transfusion Centre (CNTS), Ouagadougou, Burkina Faso
Mahamoudou Sanou
Cyrille Bisseye
Marilène Inès Kaboré
Yacouba K Nebie
Kisito Kienou
Alice Kiba
Honorine Dahourou
Siaka Ouattara
Jean Didier Zongo
Jacques Simporé
National Blood Transfusion Service · NGCentre National de Semences Forestières · BFUniversité Joseph Ki-Zerbo · BF

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe high prevalence of numerous transfusion-transmitted infectious diseases such as human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV) and syphilis in sub-Saharan Africa affects the safety of blood for recipients. This study was undertaken with the aim of determining the seroprevalence of HIV, HCV, HBV, syphilis and socio-demographic risk factors associated with blood donation in a new regional blood transfusion centre in Burkina Faso. MATERIAL AND

methodsSera samples were screened for hepatitis B surface antigen (HBsAg), antibodies to HCV, HIV types 1 and 2 and to Treponema pallidum using enzyme-linked immunosorbent assays and Rapid Plasma Reagin test (RPR) respectively. All the reactive samples for HIV, HBsAg, and HCV were confirmed using a second enzyme-linked immunosorbent assays. Antibodies to Treponema pallidum were confirmed with a Treponema pallidum haemagglutination test (TPHA).

resultsFrom the total of 4,520 blood donors in 2009, 1,348 (29.82%) were infected with at least one pathogen and 149 (3.30%) had serological evidence of multiple infections. The overall seroprevalence rate of HIV, HBV, HCV and syphilis was 2.21%, 14.96%, 8.69% and 3.96%, respectively. Among blood donors with multiples infections, the most common dual or triple combinations were HBsAg-HCV (1.39%), HBsAg-syphilis (0.66%) and HBsAg-HCV-syphilis (0.11%). The highest prevalences of HBsAg and HIV were found among blood donors from rural areas and in the age groups of 20-29 years and >40 years old, respectively.

conclusionHBV and HCV remain the greatest threats to blood safety in Burkina Faso. Strict selection and retention of voluntary, non-remunerated low-risk blood donors are recommended to improve blood safety in the regional blood transfusion centre of Koudougou.

Indexed as

HIV SeroprevalenceAdultBlood DonorsBurkina FasoFemaleHepatitis BHepatitis CHIV InfectionsHumansMaleRetrospective StudiesRisk FactorsSeroepidemiologic StudiesSyphilisYoung Adult

Identifiers

PMID21839011
PMCPMC3200412
OpenAlexW2161302056

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.