ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2011
Echocardiographic evaluation of cardiac structure and function during exercise training in the developing Sprague-Dawley rat.
Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Realistic Aspects of Cardiac Ultrasound in Rats: Practical Tips for Improved Examination.Journal of imaging · 2024Review
- Article
- The Changes of Heart miR-1 and miR-133 Expressions following Physiological Hypertrophy Due to Endurance Training.Cell journal · 2020Article
- Regulation of PI3K and Hand2 gene on physiological hypertrophy of heart following high-intensity interval, and endurance training.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2019Article
- Combination of ketamine and xylazine exacerbates cardiac dysfunction in severely scalded rats during the shock stage.Experimental and therapeutic medicine · 2013Article
- Effects of Calorie Restriction and Voluntary Exercise on Doxorubicin-Induced Cardiotoxicity.Integrative cancer therapiesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Echocardiography is a widely used evaluation tool in cardiovascular research. Although rats are a common model in such research, normal echocardiographic values for young, developing rats have not been established. Furthermore, whether exercise during the developmental phase of the lifespan affects the structure or function of the heart is unclear. Male Sprague-Dawley rat pups (21 d) were assigned randomly to a nonexercise or voluntary exercise group for 12 wk. Echocardiograms were obtained before and at weekly intervals during the 12-wk observation period. Maturation resulted in changes in many echocardiographically derived variables, whereas voluntary exercise failed to alter the development of cardiac structure or function. This study provides normal echocardiographic variables for developing male rats and provides evidence that exercise during the developmental phase of the lifespan has little effect on cardiac morphology and function as assessed by echocardiography.
Indexed as
Identifiers
21838971PMC3148638What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.