ArticleBMC plant biology2011
Resistance to Plasmopara viticola in a grapevine segregating population is associated with stilbenoid accumulation and with specific host transcriptional responses.
Article in BMC plant biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed, 110 citations in OpenAlex.
- Multiple, simultaneous abiotic stresses differentially impact downy mildew infection in grapevine.Tree physiology · 2026Article
- A core Plasmopara viticola effector attenuates the DNA-binding activity of bZIP transcription factor to compromise plant immunity.The Plant journal : for cell and molecular biology · 2025Article
- Synergistic activation of grapevine defense mechanisms against downy mildew byFrontiers in plant science · 2025Article
- The Transcriptional Landscape of Berry Skin in Red and White PIWI ("Pilzwiderstandsfähig") Grapevines Possessing QTLs for Partial Resistance to Downy and Powdery Mildews.Plants (Basel, Switzerland) · 2024Article
- The Interactions between Two Fungal EndophytesJournal of fungi (Basel, Switzerland) · 2023Article
- Deciphering Plant-Induced Responses towardJournal of fungi (Basel, Switzerland) · 2023Article
- The mature phyllosphere microbiome of grapevine is associated with resistance againstFrontiers in microbiology · 2023Article
- Phenotyping for QTL identification: A case study of resistance toFrontiers in plant science · 2022Review
- Transcriptomic and metabolomic integration as a resource in grapevine to study fruit metabolite quality traits.Frontiers in plant science · 2022Article
- Review
- Vitis OneGenE: A Causality-Based Approach to Generate Gene Networks inBiomolecules · 2021Article
- Grapevine Rpv3-, Rpv10- and Rpv12-mediated defense responses against Plasmopara viticola and the impact of their deployment on fungicide use in viticulture.BMC plant biology · 2021Article
- Trichoderma spp. volatile organic compounds protect grapevine plants by activating defense-related processes against downy mildew.Physiologia plantarum · 2021Article
- Proteomic analysis of early-stage incompatible and compatible interactions between grapevine and P. viticola.Horticulture research · 2021Article
- Article
- Mono-Locus and Pyramided Resistant Grapevine Cultivars Reveal Early Putative Biomarkers Upon Artificial Inoculation WithFrontiers in plant science · 2021Article
- Plasmopara viticola infection affects mineral elements allocation and distribution in Vitis vinifera leaves.Scientific reports · 2020Article
- Integrating metabolomics and targeted gene expression to uncover potential biomarkers of fungal/oomycetes-associated disease susceptibility in grapevine.Scientific reports · 2020Article
- Semi-Targeted Metabolomics to Validate Biomarkers of Grape Downy Mildew Infection Under Field Conditions.Plants (Basel, Switzerland) · 2020Article
- Transcriptional regulation of stilbene synthases in grapevine germplasm differentially susceptible to downy mildew.BMC plant biology · 2019Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDowny mildew, caused by the oomycete Plasmopara viticola, is a serious disease in Vitis vinifera, the most commonly cultivated grapevine species. Several wild Vitis species have instead been found to be resistant to this pathogen and have been used as a source to introgress resistance into a V. vinifera background. Stilbenoids represent the major phytoalexins in grapevine, and their toxicity is closely related to the specific compound. The aim of this study was to assess the resistance response to P. viticola of the Merzling × Teroldego cross by profiling the stilbenoid content of the leaves of an entire population and the transcriptome of resistant and susceptible individuals following infection.
resultsA three-year analysis of the population's response to artificial inoculation showed that individuals were distributed in nine classes ranging from total resistance to total susceptibility. In addition, quantitative metabolite profiling of stilbenoids in the population, carried out using HPLC-DAD-MS, identified three distinct groups differing according to the concentrations present and the complexity of their profiles. The high producers were characterized by the presence of trans-resveratrol, trans-piceid, trans-pterostilbene and up to thirteen different viniferins, nine of them new in grapevine.Accumulation of these compounds is consistent with a resistant phenotype and suggests that they may contribute to the resistance response.A preliminary transcriptional study using cDNA-AFLP selected a set of genes modulated by the oomycete in a resistant genotype. The expression of this set of genes in resistant and susceptible genotypes of the progeny population was then assessed by comparative microarray analysis.A group of 57 genes was found to be exclusively modulated in the resistant genotype suggesting that they are involved in the grapevine-P. viticola incompatible interaction. Functional annotation of these transcripts revealed that they belong to the categories defense response, photosynthesis, primary and secondary metabolism, signal transduction and transport.
conclusionsThis study reports the results of a combined metabolic and transcriptional profiling of a grapevine population segregating for resistance to P. viticola. Some resistant individuals were identified and further characterized at the molecular level. These results will be valuable to future grapevine breeding programs.
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