ArticleJournal of medical virology2011
Detection and genetic diversity of human metapneumovirus in hospitalized children with acute respiratory infections in India.
Article in Journal of medical virology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Human metapneumovirus in patients hospitalized with acute respiratory infections: A meta-analysis.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2016Pooled it
- Trends of severe human metapneumovirus infections in India.BMC infectious diseases · 2026Article
- Burden of Human Metapneumovirus in India: Epidemiological Trends and Clinical Impact.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2026Review
- Clinical and epidemiological characteristics of human metapneumovirus in children in Hangzhou, China.Virology journal · 2025Article
- Review: Knowledge Gained and Gaps in Understanding in the 25 Years Since Human Metapneumovirus Was First Identified as a Cause of Human Disease.The Journal of infectious diseases · 2025Review
- Review
- Molecular detection and genotyping of HMPV in patients with severe acute respiratory infection in India.Annals of medicine · 2024Article
- Human metapneumovirus (hMPV): an associated etiology of severe acute respiratory infection in children of Eastern Uttar Pradesh, India.Access microbiology · 2024Article
- Multicenter epidemiological investigation and genetic characterization of respiratory syncytial virus and metapneumovirus infections in the pre-pandemic 2018-2019 season in northern and central Italy.Clinical and experimental medicine · 2023Article
- Molecular investigation of human metapneumovirus in children with acute respiratory infections in Chennai, South India, from 2016-2018.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Article
- The role of lipid rafts in cell entry of human metapneumovirus.Journal of medical virology · 2019Article
- Comparison of the Panther Fusion and Allplex assays for the detection of respiratory viruses in clinical samples.PloS one · 2019Article
- Human Metapneumovirus and Other Respiratory Viral Infections during Pregnancy and Birth, Nepal.Emerging infectious diseases · 2017Article
- 180-Nucleotide Duplication in the G Gene ofFrontiers in microbiology · 2017Article
- Human metapneumovirus epidemiological and evolutionary patterns in Coastal Kenya, 2007-11.BMC infectious diseases · 2016Article
- Factors associated with the time to the first wheezing episode in infants: a cross-sectional study from the International Study of Wheezing in Infants (EISL).NPJ primary care respiratory medicine · 2016Article
- Development of real-time RT-PCR for detection of human metapneumovirus and genetic analysis of circulating strains (2009-2011) in Pune, India.Archives of virology · 2014Article
- Fungal colonization with Pneumocystis correlates to increasing chloride channel accessory 1 (hCLCA1) suggesting a pathway for up-regulation of airway mucus responses, in infant lungs.Results in immunology · 2014Article
- Human metapneumovirus: insights from a ten-year molecular and epidemiological analysis in Germany.PloS one · 2014Article
- Article
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
Human metapneumovirus (hMPV) causes acute respiratory infections in children and adults. It is classified into two major genetic lineages and each lineage into two sublineages. The purpose of the study was to identify and characterize hMPV in children who presented to the All India Institute of Medical Sciences, New Delhi, India with acute respiratory infection from April 2005 to March 2007. By reverse-transcription polymerase chain reaction, hMPV was detected in 21 (3%) of the 662 nasopharyngeal samples from children with acute respiratory infection and in none of the 120 control children. Seven of the 21 (33%) children infected with hMPV required hospital admission for pneumonia or bronchiolitis. Most hMPV detections were during the winter and spring seasons. The majority (67%, 11/21) of children positive for hMPV were within 24 months of age. Phylogenetic analysis of partial F and N gene and the full G gene sequences showed three sub-lineages of hMPV circulated during the study period, B1, B2, and the novel sub-lineage A2b. The circulation pattern of hMPV genotypes varied by season. Comparison of the F and G genes of eight strains revealed incongruencies in lineage assignments, raising the possibility that recombination had occurred. Sequence analysis also revealed the F gene was relatively conserved whereas the G gene was more variable between the A and B lineages. This study demonstrates that hMPV is an important contributor to acute respiratory infection in children in India, resulting in both outpatient visits and hospitalizations.
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