ArticleJournal of transplantation2011
Primary graft failure after heart transplantation.
Article in Journal of transplantation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 144 citations in OpenAlex.
- Meta-Analysis of Durable Compared to Temporary Left Ventricular Assist Devices Compared to Venoarterial Extracorporeal Membrane Oxygenation for Bridging to Heart Transplantation or Treatment of Primary Graft Dysfunction.Reviews in cardiovascular medicine · 2025Pooled it
- Review
- Ex Vivo Hypothermic Perfusion Enables 48-Hour Heart Preservation and Bench-Top Functional Recovery via Normothermic Reperfusion in a Porcine Model.Journal of the American Heart Association · 2026Article
- Incidence, predictors and outcomes following primary graft dysfunction after cardiac transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Gene expression analysis of primary graft dysfunction in adult heart transplant recipients: A cohort study.JHLT open · 2025Article
- Primary graft dysfunction in heart transplantation: the challenge to survival.Journal of cardiothoracic surgery · 2024Review
- Application of nanomaterials in heart transplantation: a narrative review.Journal of thoracic disease · 2024Review
- Heart Transplantation.Journal of clinical medicine · 2024Review
- Risk prediction models of primary graft dysfunction in cardiac transplant patients: a need to improve?Frontiers in cardiovascular medicine · 2024Article
- Pharmacological inhibition of the cysteine protease cathepsin C improves graft function after heart transplantation in rats.Journal of translational medicine · 2023Article
- The role of CD38 in ischemia reperfusion injury in cardiopulmonary bypass and thoracic transplantation: a narrative review.Journal of thoracic disease · 2023Review
- Unloading, ablation, bridging and transplant: different indications and treatments using the Impella 5.5 as longer-term circulatory support in one patient-an interdisciplinary case report.European heart journal. Case reports · 2023Article
- Severe and Moderate Primary Graft Dysfunction in Adult Heart Recipients.Brazilian journal of cardiovascular surgery · 2023Article
- Targeting IL-6 to prevent cardiac allograft rejection.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022Review
- Failure to rescue: obesity increases the risk of mortality following early graft failure in heart transplantation in UNOS database patients.Interactive cardiovascular and thoracic surgery · 2022Article
- Plasma kallikrein predicts primary graft dysfunction after heart transplant.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2021Article
- Circulating growth differentiation factor-15 as a novel biomarker in heart transplant.ESC heart failure · 2021Article
- Risk factors for heart transplant survival with greater than 5 h of donor heart ischemic time.Journal of cardiac surgery · 2021Article
- New Insights in Molecular Mechanisms and Pathophysiology of Ischemia-Reperfusion Injury 2.0: An Updated Overview.International journal of molecular sciences · 2020Article
- Intraoperative hemoglobin level and primary graft dysfunction in adult heart transplantation.General thoracic and cardiovascular surgery · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary graft failure (PGF) is a devastating complication that occurs in the immediate postoperative period following heart transplantation. It manifests as severe ventricular dysfunction of the donor graft and carries significant mortality and morbidity. In the last decade, advances in pharmacological treatment and mechanical circulatory support have improved the outlook for heart transplant recipients who develop this complication. Despite these advances in treatment, PGF is still the leading cause of death in the first 30 days after transplantation. In today's climate of significant organ shortages and growing waiting lists, transplant units worldwide have increasingly utilised "marginal donors" to try and bridge the gap between "supply and demand." One of the costs of this strategy has been an increased incidence of PGF. As the threat of PGF increases, the challenges of predicting and preventing its occurrence, as well as the identification of more effective treatment modalities, are vital areas of active research and development.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.