ArticleJournal of virology2011
Novel adenoviruses in wild primates: a high level of genetic diversity and evidence of zoonotic transmissions.
Article in Journal of virology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 2 syntheses or guidelines pooled it, 107 citations in OpenAlex.
- Are adenoviruses zoonotic? A systematic review of the evidence.Emerging microbes & infections · 2019Pooled it
- Reverse zoonotic disease transmission (zooanthroponosis): a systematic review of seldom-documented human biological threats to animals.PloS one · 2014Pooled it
- Novel polyomaviruses of nonhuman primates: genetic and serological predictors for the existence of multiple unknown polyomaviruses within the human population.PLoS pathogens · 2013Trial
- Review
- Early-life infection dynamics and genomic diversity of adenoviruses in a wild primate (Microbial genomics · 2025Article
- Updated practice for detection of viral infections in breeding macaques.Zoological research · 2025Review
- Novel Mastadenovirus Infection as Cause of Pneumonia in Imported Black-and-White Colobuses (Colobus guereza), Thailand.Emerging infectious diseases · 2024Article
- Reverse Zoonotic Transmission of SARS-CoV-2 and Monkeypox Virus: A Comprehensive Review.Journal of microbiology (Seoul, Korea) · 2024Review
- Isolation of a recombinant simian adenovirus encoding the human adenovirus G52 hexon suggests a simian origin for human adenovirus G52.Journal of virology · 2024Article
- Potentially Zoonotic Enteric Infections in Gorillas and Chimpanzees, Cameroon and Tanzania.Emerging infectious diseases · 2024Article
- The adenovirus DNA-binding protein DBP.Journal of virology · 2024Review
- Detection and Molecular Characterization of Adenoviruses in Captive and Free-Roaming African Green Monkeys (Viruses · 2023Article
- Higher convergence of human-great ape enteric eukaryotic viromes in central African forest than in a European zoo: a One Health analysis.Nature communications · 2023Article
- Pathologic characteristics of infectious diseases in macaque monkeys used in biomedical and toxicologic studies.Journal of toxicologic pathology · 2023Review
- A Review on Zoonotic Pathogens Associated with Non-Human Primates: Understanding the Potential Threats to Humans.Microorganisms · 2023Review
- Viruses in sanctuary chimpanzees across Africa.American journal of primatology · 2023Article
- Adenoviruses in medicine: innocuous pathogen, predator, or partner.Trends in molecular medicine · 2023Review
- Simian adenoviruses: Molecular and serological survey in monkeys and humans in Thailand.One health (Amsterdam, Netherlands) · 2022Article
- Article
- Human-Borne Pathogens: Are They Threatening Wild Great Ape Populations?Veterinary sciences · 2022Review
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 13 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adenoviruses (AdVs) broadly infect vertebrate hosts, including a variety of nonhuman primates (NHPs). In the present study, we identified AdVs in NHPs living in their natural habitats, and through the combination of phylogenetic analyses and information on the habitats and epidemiological settings, we detected possible horizontal transmission events between NHPs and humans. Wild NHPs were analyzed with a pan-primate AdV-specific PCR using a degenerate nested primer set that targets the highly conserved adenovirus DNA polymerase gene. A plethora of novel AdV sequences were identified, representing at least 45 distinct AdVs. From the AdV-positive individuals, 29 nearly complete hexon genes were amplified and, based on phylogenetic analysis, tentatively allocated to all known human AdV species (Human adenovirus A to Human adenovirus G [HAdV-A to -G]) as well as to the only simian AdV species (Simian adenovirus A [SAdV-A]). Interestingly, five of the AdVs detected in great apes grouped into the HAdV-A, HAdV-D, HAdV-F, or SAdV-A clade. Furthermore, we report the first detection of AdVs in New World monkeys, clustering at the base of the primate AdV evolutionary tree. Most notably, six chimpanzee AdVs of species HAdV-A to HAdV-F revealed a remarkably close relationship to human AdVs, possibly indicating recent interspecies transmission events.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.