Evidence map›Paper›PMID 21835681›Full record

ReviewTrends in cognitive sciences2011

Genetics of emotion.

Laura Bevilacqua, David Goldman

Open access · greenAbstract readReview
In one paragraph

Review in Trends in cognitive sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 61 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Early event-related potentials to emotional faces differ for adults with autism spectrum disorder and by serotonin transporter genotype.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2016
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Laura BevilacquaLaboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD 20852, USA.
David Goldman
National Institute on Alcohol Abuse and Alcoholism · US

Funding

Integrative genetics of behavior with high throughput technologiesZIAAA000301 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI GOLDMAN, DAVID · 2009 to 2025
$68.6M
Integrative genetics with high throughput, multiplex genZ01AA000301 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI GOLDMAN, DAVID · 1999 to 2008
$5.2M
Intramural NIH HHS Z01 AA000301Intramural NIH HHS Z99 AA999999
6 · The paper itself

Abstract

Emotion is critical to most aspects of human behavior, and individual differences in systems recruited to process emotional stimuli, expressed as variation in emotionality, are characteristic of several neuropsychiatric disorders. We examine the genetic origins of individual differences in emotion processing by focusing on functional variants at five genes: catechol-O-methyltransferase (COMT), serotonin transporter (SLC6A4), neuropeptide Y (NPY), a glucocorticoid receptor-regulating co-chaperone of stress proteins (FKBP5) and pituitary adenylate cyclase-activating polypeptide receptor (ADCYAP1R1). These represent a range of effects of genes on emotion as well as the variety of mechanisms and factors, such as stress, that modify these effects. The new genomic era of genome-wide association studies (GWAS) and deep sequencing may yield a wealth of new loci modulating emotion. The effects of these genes can be validated by neuroimaging, neuroendocrine and other studies accessing intermediate phenotypes, deepening our understanding of mechanisms of emotion and variation in emotionality.

Indexed as

GeneticsCatechol O-MethyltransferaseEmotionsGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansMood DisordersNeuroimagingNeuropeptide YReceptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type ISerotonin Plasma Membrane Transport ProteinsTacrolimus Binding Protein 5Tacrolimus Binding ProteinsADCYAP1R1 protein, humanCatechol O-MethyltransferaseNeuropeptide YReceptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type ISerotonin Plasma Membrane Transport ProteinsSLC6A4 protein, humanTacrolimus Binding Protein 5Tacrolimus Binding Proteins

Identifiers

PMID21835681
PMCPMC3408019
OpenAlexW2017069230

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.