ArticleGastrointestinal endoscopy2011
Capsule endoscopy in nonresponsive celiac disease.
Article in Gastrointestinal endoscopy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- Guideline
- ACG clinical guidelines: diagnosis and management of celiac disease.The American journal of gastroenterology · 2013Guideline
- Evaluating Responses to Gluten Challenge: A Randomized, Double-Blind, 2-Dose Gluten Challenge Trial.Gastroenterology · 2021Trial
- First Brazilian expert consensus for video capsule endoscopy and balloon-assisted enteroscopy.Clinics (Sao Paulo, Brazil) · 2026Article
- Malignancies in Celiac Disease-A Hidden Threat with Diagnostic Pitfalls.Biomedicines · 2025Review
- Could Capsule Endoscopy Be Useful in Detection of Suspected Small Bowel Bleeding and IBD-10 Years of Single Center Experience.Diagnostics (Basel, Switzerland) · 2024Article
- Guidelines for best practices in monitoring established coeliac disease in adult patients.Nature reviews. Gastroenterology & hepatology · 2024Review
- The Evolving Landscape of Biomarkers in Celiac Disease: Leading the Way to Clinical Development.Frontiers in immunology · 2021Review
- Optimising the use of small bowel endoscopy: a practical guide.Frontline gastroenterology · 2019Review
- Role of capsule endoscopy in suspected celiac disease: A European multi-centre study.World journal of gastroenterology · 2017Observational
- Investigation of Small Bowel Abnormalities in HIV-Infected Patients Using Capsule Endoscopy.Gastroenterology research and practice · 2017Article
- Small bowel capsule endoscopy: Where are we after almost 15 years of use?World journal of gastrointestinal endoscopy · 2015Review
- Capsule endoscopy: current practice and future directions.World journal of gastroenterology · 2014Review
- Association between celiac disease and iron deficiency in Caucasians, but not non-Caucasians.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2013Article
- Quantitative estimates of motility from videocapsule endoscopy are useful to discern celiac patients from controls.Digestive diseases and sciences · 2012Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundNonresponsive celiac disease (CD) is defined by persistent or recurrent symptoms, common after treatment with a gluten-free diet (GFD).
objectiveTo evaluate the utility of capsule endoscopy (CE) in nonresponsive CD.
designCase-control study.
settingTertiary-care center. PATIENTS: Forty-two consecutive patients with nonresponsive CD and 84 age- and sex-matched CD-free controls who underwent CE were included. In addition, capsules taken after treatment with a GFD were retrospectively evaluated in 30 patients with uncomplicated CD.
interventionCE. MAIN OUTCOME MEASUREMENTS: Diagnostic accuracy of CE for the detection of mucosal abnormalities in nonresponsive CD.
resultsMacroscopic features of villous atrophy were detected in 13 of 42 patients (31%) with nonresponsive CD compared with none among 84 CD-free controls and 14 of 30 patients (47%) with uncomplicated CD. Among nonresponsive CD cases, the overall sensitivity and specificity of CE for the detection of any degree of villous atrophy as graded by histology were 56% and 85%, respectively. Single or multiple erosions/ulcerations of the gut were observed in 19% of nonresponsive CD patients, 18% of CD-free controls, and 31% of patients with uncomplicated CD (P = .35). The presence of erosions/ulcerations was associated with increased aspirin/nonsteroidal anti-inflammatory drug use in nonresponsive CD (P =.05). Two severe complications (ulcerative jejunitis and adenocarcinoma) were detected by CE in nonresponsive CD. LIMITATIONS: Single-center, retrospective study.
conclusionsMucosal abnormalities were observed by CE in patients with both nonresponsive CD and uncomplicated CD. CE can detect severe complications in patients with nonresponsive CD.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.