Trial reportImplementation science : IS2011
Improving hypertension management through pharmacist prescribing; the rural Alberta clinical trial in optimizing hypertension (Rural RxACTION): trial design and methods.
Trial report in Implementation science : IS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00878566 (Alberta Clinical Trial in Optimizing Hypertension), which is not on this map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Alberta Clinical Trial in Optimizing Hypertension: The RxAction Study
Who cites it
11 citing papers in PubMed, 31 citations in OpenAlex.
- Stroke Risk Reduction in Atrial Fibrillation Through Pharmacist Prescribing: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Effects of Montmorency Tart Cherry and Blueberry Juice on Cardiometabolic and Other Health-Related Outcomes: A Three-Arm Placebo Randomized Controlled Trial.International journal of environmental research and public health · 2022Trial
- Effects of Montmorency Tart Cherry and Blueberry Juice on Cardiometabolic Outcomes in Healthy Individuals: Protocol for a 3-Arm Placebo Randomized Controlled Trial.International journal of environmental research and public health · 2021Article
- Feasibility of a Web-Based Platform (Trial My App) to Efficiently Conduct Randomized Controlled Trials of mHealth Apps For Patients With Cardiovascular Risk Factors: Protocol For Evaluating an mHealth App for Hypertension.JMIR research protocols · 2021Article
- Article
- Pay-for-performance remuneration for pharmacist prescribers' management of hypertension: A substudy of the RxACTION trial.Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC · 2016Article
- A scoping review of research on the prescribing practice of Canadian pharmacists.Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC · 2015Article
- The expanding scope of pharmacists' practice: implications for physicians.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2013Article
- Another hypertension visit.Canadian family physician Medecin de famille canadien · 2012Article
- Stories from the trenches: Experiences of Alberta pharmacists in obtaining additional prescribing authority.Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC · 2012Article
- Evaluating the potential for pharmacists to prescribe oral anticoagulants for atrial fibrillation.Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPCArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with hypertension continue to have less than optimal blood pressure control, with nearly one in five Canadian adults having hypertension. Pharmacist prescribing is gaining favor as a potential clinically efficacious and cost-effective means to improve both access and quality of care. With Alberta being the first province in Canada to have independent prescribing by pharmacists, it offers a unique opportunity to evaluate outcomes in patients who are prescribed antihypertensive therapy by pharmacists.
methodsThe study is a randomized controlled trial of enhanced pharmacist care, with the unit of randomization being the patient. Participants will be randomized to enhanced pharmacist care (patient identification, assessment, education, close follow-up, and prescribing/titration of antihypertensive medications) or usual care. Participants are patients in rural Alberta with undiagnosed/uncontrolled blood pressure, as defined by the Canadian Hypertension Education Program. The primary outcome is the change in systolic blood pressure between baseline and 24 weeks in the enhanced-care versus usual-care arms. There are also three substudies running in conjunction with the project examining different remuneration models, investigating patient knowledge, and assessing health-resource utilization amongst patients in each group. DISCUSSION: To date, one-third of the required sample size has been recruited. There are 15 communities and 17 pharmacists actively screening, recruiting, and following patients. This study will provide high-level evidence regarding pharmacist prescribing.
trial registrationClinicaltrials.gov NCT00878566.
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