Evidence map›Paper›PMID 21834914›Full record

ArticlePain medicine (Malden, Mass.)2011

Improving the pharmacologic management of pain in older adults: identifying the research gaps and methods to address them.

M Cary Reid, David A Bennett, Wen G Chen, Basil A Eldadah, John T Farrar, Bruce Ferrell, Rollin M Gallagher, Joseph T Hanlon, Keela Herr, Susan D Horn and 12 more

Abstract readCase ReportsConsensus Development Conference, NIH
In one paragraph

Article in Pain medicine (Malden, Mass.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Trial
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  7. A Scoping Review of Nursing's Contribution to the Management of Patients with Pain and Opioid Misuse.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Age and Sex Differences in Acute and Osteoarthritis-Like Pain Responses in Rats.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Depression, Anxiety, and Pain among Newly Admitted Nursing Home Residents.The journal of nursing home research sciences · 2019
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

M Cary ReidDivision of Geriatrics and Gerontology, Weill Cornell Medical Center, 525 East 68th Street, Box 39, New York, NY 10065, USA. mcr2004@med.cornell.edu
David A Bennett
Wen G Chen
Basil A Eldadah
John T Farrar
Bruce Ferrell
Rollin M Gallagher
Joseph T Hanlon
Keela Herr
Susan D Horn
Charles E Inturrisi
Salma Lemtouni
Yu Woody Lin
Kaleb Michaud
R Sean Morrison
Tuhina Neogi
Linda L Porter
Daniel H Solomon
Michael Von Korff
Karen Weiss
James Witter
Kevin L Zacharoff

Funding

INSTITUTIONAL CLINICAL AND TRANSLATIONAL SCIENCE AWARDUL1RR024134 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2006 to 2011
$70.4M
SUPPLEMENT TO RUSH ALZHEIMERS DISEASE CENTER COREP30AG010161 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 1991 to 2020
$49.1M
EPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3M
WOMENS HEALTH ACROSS THE NATION--COORDINATING CENTERU01AG012553 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BROOKS, MARIA MORI · 1994 to 2019
$37.7M
VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Caterina Rosano · 2004 to 2026
$28.6M
Residing in the Community with Dementia at the End of Life: Understanding Hospice Use and Residential SettingP30AG028741 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ORNA INTRATOR · 2010 to 2026
$21.9M
RISK FACTORS, PATHOLOGY, AND CLINICAL EXPRESSIONS OF ADR01AG015819 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 1998 to 2024
$21.4M
Pilot CoreP30AG022845 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Manney Carrington Reid, ELAINE WETHINGTON · 2003 to 2026
$15.2M
Pitt Integrated Clinical and Geroscience Research Training ProgramT32AG021885 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Aditi U Gurkar · 2003 to 2026
$6.7M
Improving pain and function in hip fractureR01AG030141 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MORRISON, R. SEAN · 2008 to 2013
$3.8M
Transition to Long-Term Opioid Use Among Older Adults with Chronic PainR01AG034181 · NIA · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI VON KORFF, MICHAEL R · 2010 to 2014
$2.8M
Cancer Pain in Elders: Promoting EBPs in HospicesR01CA115363 · NCI · UNIVERSITY OF IOWA · PI HERR, KEELA A · 2005 to 2010
$2.7M
AHRQ HHS K12 HS019461AHRQ HHS K12HS019461AHRQ HHS R01 HS017695AHRQ HHS R01HS017695AHRQ HHS R01 HS018721AHRQ HHS R01HS018721NCI NIH HHS R01 CA115363NCI NIH HHS R01CA115363NCRR NIH HHS UL1 RR024134NCRR NIH HHS UL1RR024134NIAMS NIH HHS K23 AR055127NIAMS NIH HHS K23AR055127NIAMS NIH HHS K24 AR055989NIAMS NIH HHS K24AR055989NIAMS NIH HHS RC1 AR058601NIAMS NIH HHS RC1AR058601NIA NIH HHS K07 AG033174NIA NIH HHS K07AG033174NIA NIH HHS K24 AG022345NIA NIH HHS K24AG022345NIA NIH HHS P30 AG010161NIA NIH HHS P30 AG022845NIA NIH HHS P30 AG024827NIA NIH HHS P30AG024827NIA NIH HHS P30 AG028741NIA NIH HHS P30AG028741NIA NIH HHS P30AG10161NIA NIH HHS P30 AG22845NIA NIH HHS R01 AG015819NIA NIH HHS R01 AG017917NIA NIH HHS R01 AG030141NIA NIH HHS R01AG030141NIA NIH HHS R01 AG034056NIA NIH HHS R01AG034056NIA NIH HHS R01 AG034181NIA NIH HHS R01AG034181NIA NIH HHS R01AG15819NIA NIH HHS R01AG17917NIA NIH HHS R56 AG027017NIA NIH HHS R56AG027017NIA NIH HHS T32 AG021885NIA NIH HHS T32AG021885NIA NIH HHS U01 AG012553NIA NIH HHS U01AG012553NIDA NIH HHS R01 DA022557NIDA NIH HHS R01DA022557NIDA NIH HHS RC2 DA028928NIDA NIH HHS RC2DA028928NIMH NIH HHS R34 MH082682NIMH NIH HHS R34MH082682NINR NIH HHS R01 NR010135NINR NIH HHS R01NR010135NINR NIH HHS T32 NR011147NINR NIH HHS T32NR011147
6 · The paper itself

Abstract

objectiveThere has been a growing recognition of the need for better pharmacologic management of chronic pain among older adults. To address this need, the National Institutes of Health Pain Consortium sponsored an "Expert Panel Discussion on the Pharmacological Management of Chronic Pain in Older Adults" conference in September 2010 to identify research gaps and strategies to address them. Specific emphasis was placed on ascertaining gaps regarding use of opioid and nonsteroidal anti-inflammatory medications because of continued uncertainties regarding their risks and benefits.

designEighteen panel members provided oral presentations; each was followed by a multidisciplinary panel discussion. Meeting transcripts and panelists' slide presentations were reviewed to identify the gaps and the types of studies and research methods panelists suggested could best address them.

resultsFifteen gaps were identified in the areas of treatment (e.g., uncertainty regarding the long-term safety and efficacy of commonly prescribed analgesics), epidemiology (e.g., lack of knowledge regarding the course of common pain syndromes), and implementation (e.g., limited understanding of optimal strategies to translate evidence-based pain treatments into practice). Analyses of data from electronic health care databases, observational cohort studies, and ongoing cohort studies (augmented with pain and other relevant outcomes measures) were felt to be practical methods for building an age-appropriate evidence base to improve the pharmacologic management of pain in later life.

conclusionAddressing the gaps presented in the current report was judged by the panel to have substantial potential to improve the health and well-being of older adults with chronic pain.

Indexed as

AgedAged, 80 and overAnalgesiaAnalgesicsBiomedical ResearchEvidence-Based MedicineHumansIntractable PainAnalgesics

Identifiers

PMID21834914
PMCPMC3173592

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.