ArticleAIDS and behavior2011
Medication adherence: tailoring the analysis to the data.
Article in AIDS and behavior, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Digital interventions to improve adherence to maintenance medication in asthma.The Cochrane database of systematic reviews · 2022Pooled it
- Necessity and concerns beliefs and HIV medication adherence: a systematic review.Journal of behavioral medicine · 2020Pooled it
- Including the Household: Individual, Community and Household Factors Affecting Antiretroviral Therapy Adherence After ART Initiation in Cape Town, South Africa.AIDS and behavior · 2024Trial
- Evaluation of Sexual Risk Behavior Among Study Participants in the TDF2 PrEP Study Among Heterosexual Adults in Botswana.Journal of acquired immune deficiency syndromes (1999) · 2016Trial
- The Impact of a Household Intervention on ART Adherence and Household HIV Competency for People Living with HIV: Results from a Cluster-Randomised Controlled Trial in Cape Town, South Africa.AIDS and behavior · 2026Article
- A latent-class heteroskedastic hurdle trajectory model: patterns of adherence in obstructive sleep apnea patients on CPAP therapy.BMC medical research methodology · 2021Article
- Trends in HIV Treatment Adherence Before and After HIV Status Disclosure to Adolescents in Botswana.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2020Article
- Association of Medication Adherence with Hospital Utilization and Costs Among Elderly with Diabetes Enrolled in a State Pharmaceutical Assistance Program.Journal of managed care & specialty pharmacy · 2020Observational
- Statistical considerations for medication adherence research.Current medical research and opinion · 2020Article
- Scoping review and bibliometric analysis of Big Data applications for Medication adherence: an explorative methodological study to enhance consistency in literature.BMC health services research · 2020Article
- Adherence to Adjuvant Endocrine Therapy in Insured Black and White Breast Cancer Survivors: Exploring Adherence Measures in Patient Data.Journal of managed care & specialty pharmacy · 2019Article
- Trends in Nonlipid Cardiovascular Disease Risk Factor Management in the Women's Interagency HIV Study and Association with Adherence to Antiretroviral Therapy.AIDS patient care and STDs · 2016Article
- Correlation between use of antiretroviral adherence devices by HIV-infected youth and plasma HIV RNA and self-reported adherence.AIDS and behavior · 2015Article
- Increase in single-tablet regimen use and associated improvements in adherence-related outcomes in HIV-infected women.Journal of acquired immune deficiency syndromes (1999) · 2014Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The purpose of this paper is to explore more comprehensive methods to analyze antiretroviral non-adherence data. Using illustrative data and simulations, we investigated the value of using binary logistic regression (LR; dichotomized at 0% non-adherence) versus a hurdle model (combination of LR plus generalized linear model for >0% non-adherence) versus a zero-inflated negative binomial (ZINB) model (simultaneously modeling 0% non-adherence and >0% non-adherence). In simulation studies, the hurdle and ZINB models had similar power but both had higher power in comparison to LR alone. The hurdle model had higher power than ZINB in settings where covariate effects were restricted to one or the other part of the model (0% non-adherence or degree of non-adherence). Use of the hurdle and ZINB models are powerful and valuable approaches in analyzing adherence data which yield a more complete picture than LR alone. We recommend adoption of this methodology for future antiretroviral adherence research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.