ArticleFrontiers in microbiology2011
Small Regulatory RNA and Legionella pneumophila.
Article in Frontiers in microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 29 citations in OpenAlex.
- Genomic analysis ofMicrobial genomics · 2025Article
- Two-component system GacS/GacA, a global response regulator of bacterial physiological behaviors.Engineering microbiology · 2023Review
- Legionnaires' Disease in China Caused byMicroorganisms · 2023Article
- Potential probiotic approaches to control Legionella in engineered aquatic ecosystems.FEMS microbiology ecology · 2022Review
- Article
- Quorum sensing controls persistence, resuscitation, and virulence of Legionella subpopulations in biofilms.The ISME journal · 2021Article
- Small RNAs as Fundamental Players in the Transference of Information During Bacterial Infectious Diseases.Frontiers in molecular biosciences · 2020Review
- 6S RNA, a Global Regulator of Transcription.Microbiology spectrum · 2018Review
- Suppressing the CRISPR/Cas adaptive immune system in bacterial infections.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017Review
- Small Regulatory RNAs of Rickettsia conorii.Scientific reports · 2016Article
- Active and adaptive Legionella CRISPR-Cas reveals a recurrent challenge to the pathogen.Cellular microbiology · 2016Article
- Legionella pneumophila strain associated with the first evidence of person-to-person transmission of Legionnaires' disease: a unique mosaic genetic backbone.Scientific reports · 2016Article
- Transcriptome-Wide Identification of Hfq-Associated RNAs in Brucella suis by Deep Sequencing.Journal of bacteriology · 2016Article
- Sibling rivalry: related bacterial small RNAs and their redundant and non-redundant roles.Frontiers in cellular and infection microbiology · 2014Review
- Analysis of the transcriptome of Legionella pneumophila hfq mutant reveals a new mobile genetic element.Microbiology (Reading, England) · 2013Article
- Article
- Virulence phenotypes of Legionella pneumophila associated with noncoding RNA lpr0035.Infection and immunity · 2012Article
- Legionella: from protozoa to humans.Frontiers in microbiology · 2011Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Legionella pneumophila is a gram-negative bacterial species that is ubiquitous in almost any aqueous environment. It is the agent of Legionnaires' disease, an acute and often under-reported form of pneumonia. In mammals, L. pneumophila replicates inside macrophages within a modified vacuole. Many protein regulators have been identified that control virulence-related properties, including RpoS, LetA/LetS, and PmrA/PmrB. In the past few years, the importance of regulation of virulence factors by small regulatory RNA (sRNAs) has been increasingly appreciated. This is also the case in L. pneumophila where three sRNAs (RsmY, RsmZ, and 6S RNA) were recently shown to be important determinants of virulence regulation and 79 actively transcribed sRNAs were identified. In this review we describe current knowledge about sRNAs and their regulatory properties and how this relates to the known regulatory systems of L. pneumophila. We also provide a model for sRNA-mediated control of gene expression that serves as a framework for understanding the regulation of virulence-related properties of L. pneumophila.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.