ArticleFrontiers in microbiology2011
Cell viability and functionality of probiotic bacteria in dairy products.
Article in Frontiers in microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Enhancing Probiotic Performance in Food Matrices: From Strain Selection to Bioengineering.Journal of food science · 2026Review
- Purine-Degrading Lactic Acid Bacteria Isolated from Fermented Foods and Fig Fruit: Evaluation of Probiotic and Anti-Hyperuricemic Properties.Probiotics and antimicrobial proteins · 2026Article
- Spectroscopic Techniques in Bacterial Analysis: Applications of FTIR and Raman-Review.Foods (Basel, Switzerland) · 2026Review
- In vitro evaluation of Bacillus subtilis isolated from Apis mellifera for potential use as a probiotic feed additive in honeybees.Scientific reports · 2025Article
- Survivability and behavior of probiotic bacteria encapsulated by internal gelation in non-dairy matrix and In Vitro GIT conditions.PloS one · 2024Article
- A novel probiotic strain ofCurrent research in microbial sciences · 2022Article
- Ameliorative Effect of Surface Proteins of Probiotic Lactobacilli in Colitis Mouse Models.Frontiers in microbiology · 2021Article
- Postbiotics as Promising Tools for Cancer Adjuvant Therapy.Advanced pharmaceutical bulletin · 2021Article
- Safety of Probiotics: Functional Fruit Beverages and Nutraceuticals.Foods (Basel, Switzerland) · 2020Review
- Article
- Optimization of Production Parameters for Probiotic Lactobacillus Strains as Feed Additive.Molecules (Basel, Switzerland) · 2019Article
- Review
- Postbiotic metabolites produced by Lactobacillus plantarum strains exert selective cytotoxicity effects on cancer cells.BMC complementary and alternative medicine · 2019Article
- Influence of Dehydrated Wheat/Rice Cereal Matrices on Probiotic Activity ofFood technology and biotechnology · 2019Article
- Colonization and Gut Flora Modulation of Lactobacillus kefiranofaciens ZW3 in the Intestinal Tract of Mice.Probiotics and antimicrobial proteins · 2018Article
- Compositional Quality and Potential Gastrointestinal Behavior of Probiotic Products Commercialized in Italy.Frontiers in medicine · 2018Article
- Cryoprotection of probiotic bacteria with poly-γ-glutamic acid produced byJournal, genetic engineering & biotechnology · 2016Article
- Applications of Infrared and Raman Spectroscopies to Probiotic Investigation.Foods (Basel, Switzerland) · 2015Review
- Effects of milk components and food additives on survival of three bifidobacteria strains in fermented milk under simulated gastrointestinal tract conditions.Microbial ecology in health and disease · 2015Article
- Fecal microbiota transplantation: an interview with alexander khoruts.Global advances in health and medicine · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Probiotic bacteria, according to the definition adopted by the World Health Organization in 2002, are live microorganisms, which when administered in adequate amounts confer a health benefit to the host. Recent studies show that the same probiotic strain produced and/or preserved under different storage conditions, may present different responses regarding their susceptibility to the adverse conditions of the gastrointestinal tract, its capacity to adhere to the intestinal epithelium, or its immunomodulating capacity, the functionality being affected without changes in cell viability. This could imply that the control of cell viability is not always enough to guarantee the functionality (probiotic capacity) of a strain. Therefore, a new challenge arises for food technologists and microbiologists when it comes to designing and monitoring probiotic food: to be able to monitor the functionality of a probiotic microorganism throughout all the stages the strain goes through from the moment it is produced and included in the food vehicle, until the moment of consumption. Conventional methodological tools or others still to be developed must be used. The application of cell membrane functionality markers, the use of tests of resistance to intestinal barriers, the study of surface properties and the application of in vivo models come together as complementary tools to assess the actual capacity of a probiotic organism in a specific food, to exert functional effects regardless of the number of viable cells present at the moment of consumption.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.