Evidence map›Paper›PMID 21833180›Full record

ArticleFrontiers in pharmacology2010

Policies to enhance prescribing efficiency in europe: findings and future implications.

Brian Godman, William Shrank, Morten Andersen, Christian Berg, Iain Bishop, Thomas Burkhardt, Kristina Garuoliene, Harald Herholz, Roberta Joppi, Marija Kalaba and 15 more

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
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  5. Article
  6. Article
  7. Article
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  9. Article
  10. The Expiry of HumiraFrontiers in pharmacology · 2020
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
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  17. Review
  18. Rational use of medicines: Cost consideration & way forward.The Indian journal of medical research · 2016
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Brian GodmanInstitute for Pharmacological Research 'Mario Negri' Milan, Italy.
William Shrank
Morten Andersen
Christian Berg
Iain Bishop
Thomas Burkhardt
Kristina Garuoliene
Harald Herholz
Roberta Joppi
Marija Kalaba
Ott Laius
Julie Lonsdale
Rickard E Malmström
Jaana E Martikainen
Vita Samaluk
Catherine Sermet
Ulrich Schwabe
Inês Teixeira
Lesley Tilson
F Cankat Tulunay
Vera Vlahović-Palčevski
Kamila Wendykowska
Bjorn Wettermark
Corinne Zara
Lars L Gustafsson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEuropean countries need to learn from each other to address unsustainable increases in pharmaceutical expenditures.

objectiveTo assess the influence of the many supply and demand-side initiatives introduced across Europe to enhance prescribing efficiency in ambulatory care. As a result provide future guidance to countries.

methodsCross national retrospective observational study of utilization (DDDs - defined daily doses) and expenditure (Euros and local currency) of proton pump inhibitors (PPIs) and statins among 19 European countries and regions principally from 2001 to 2007. Demand-side measures categorized under the "4Es" - education engineering, economics, and enforcement.

resultsInstigating supply side initiatives to lower the price of generics combined with demand-side measures to enhance their prescribing is important to maximize prescribing efficiency. Just addressing one component will limit potential efficiency gains. The influence of demand-side reforms appears additive, with multiple initiatives typically having a greater influence on increasing prescribing efficiency than single measures apart from potentially "enforcement." There are also appreciable differences in expenditure (€/1000 inhabitants/year) between countries. Countries that have not introduced multiple demand side measures to counteract commercial pressures to enhance the prescribing of generics have seen considerably higher expenditures than those that have instigated a range of measures.

conclusionsThere are considerable opportunities for European countries to enhance their prescribing efficiency, with countries already learning from each other. The 4E methodology allows European countries to concisely capture the range of current demand-side measures and plan for the future knowing that initiatives can be additive to further enhance their prescribing efficiency.

Indexed as

drugseconomicsefficiencygenericspharmaceuticalssustainability

Identifiers

PMID21833180
PMCPMC3153015

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.