Evidence map›Paper›PMID 21832880›Full record

ReviewChannels (Austin, Tex.)

Signaling complexes of voltage-gated calcium channels.

Ray W Turner, Dustin Anderson, Gerald W Zamponi

Open access · goldAbstract readReview
In one paragraph

Review in Channels (Austin, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 47 citations in OpenAlex.

  1. Insights into3 Biotech · 2023
    Article
  2. Review
  3. Review
  4. A molecule-based genetic association approach implicates a range of voltage-gated calcium channels associated with schizophrenia.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2018
    Article
  5. Review
  6. Interaction of H2S with Calcium Permeable Channels and Transporters.Oxidative medicine and cellular longevity · 2015
    Review
  7. Article
  8. Article
  9. T-type calcium channel blockers as neuroprotective agents.Pflugers Archiv : European journal of physiology · 2014
    Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. The genomics of schizophrenia: update and implications.The Journal of clinical investigation · 2013
    Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Ray W TurnerDepartment of Cell Biology and Anatomy, Hotchkiss Brain Institute, University of Calgary, Calgary, AB Canada.
Dustin Anderson
Gerald W Zamponi
Allen Institute for Brain Science · US

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

Voltage gated calcium channels are key mediators of depolarization induced calcium entry into electrically excitable cells. There is increasing evidence that voltage gated calcium channels, like many other types of ionic channels, do not operate in isolation, but instead forms signaling complexes with signaling molecules, G protein coupled receptors, and other types of ion channels. Furthermore, there appears to be bidirectional signaling within these protein complexes, thus allowing not only for efficient translation of calcium signals into cellular responses, but also for tight control of calcium entry per se. In this review, we will focus predominantly on signaling complexes between G protein-coupled receptors and high voltage activated calcium channels, and on complexes of voltage-gated calcium channels and members of the potassium channel superfamily.

Indexed as

AnimalsCalciumCalcium ChannelsCalcium SignalingHumansReceptors, G-Protein-CoupledCalciumCalcium ChannelsReceptors, G-Protein-Coupled

Identifiers

PMID21832880
PMCPMC3265765
OpenAlexW1969945815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.