Evidence map›Paper›PMID 21832260›Full record

ReviewThe Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry2012

Genetic architecture of declarative memory: implications for complex illnesses.

Carrie E Bearden, Katherine H Karlsgodt, Peter Bachman, Theo G M van Erp, Anderson M Winkler, David C Glahn

Abstract readReview
In one paragraph

Review in The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Genome-Wide Analyses of Working-Memory Ability: A Review.Current behavioral neuroscience reports · 2014
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carrie E BeardenDepartments of Psychiatry and Biobehavioral Sciences and Psychology, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA.
Katherine H Karlsgodt
Peter Bachman
Theo G M van Erp
Anderson M Winkler
David C Glahn

Funding

Genetics of Brain Structure and FunctionR01MH078143 · NIMH · YALE UNIVERSITY · PI GLAHN, DAVID C · 2006 to 2014
$4.3M
Genetics of Brain Structure and Function: Genome-Wide AssociationR01MH083824 · NIMH · YALE UNIVERSITY · PI GLAHN, DAVID C · 2008 to 2013
$3.3M
Influence of Psychosis on Brain-Behavior Endophenotypes for Bipolar DisorderR01MH080912 · NIMH · YALE UNIVERSITY · PI GLAHN, DAVID C · 2008 to 2012
$2.6M
Response Inhibition and Dopamine Neurotransmission (RI) (4 of 8)RL1DA024853 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LONDON, EDYTHE DANICK · 2007 to 2011
$1.7M
Hypothesis Web Development for Neuropsychiatric Phenomics (6 of 8)RL1LM009833 · NLM · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PARKER, DOUGLASS STOTT · 2007 to 2011
$1.5M
Identification of endophenotypes for bipolar disorderK23MH074644 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BEARDEN, CARRIE E · 2005 to 2009
$808k
NIDA NIH HHS RL1 DA024853NIDA NIH HHS RL1-DA024853NIMH NIH HHS K23 MH074644NIMH NIH HHS K23-MH74644NIMH NIH HHS R01 MH078143NIMH NIH HHS R01-MH078143-06NIMH NIH HHS R01 MH080912NIMH NIH HHS R01-MH080912-03NIMH NIH HHS R01 MH083824NIMH NIH HHS R34 MH08929NLM NIH HHS RL1 LM009833NLM NIH HHS RL1-LM009833
6 · The paper itself

Abstract

Why do memory abilities vary so greatly across individuals and cognitive domains? Although memory functions are highly heritable, what exactly is being genetically transmitted? Here we review evidence for the contribution of both common and partially independent inheritance of distinct aspects of memory function. We begin by discussing the assessment of long-term memory and its underlying neural and molecular basis. We then consider evidence for both specialist and generalist genes underlying individual variability in memory, indicating that carving memory into distinct subcomponents may yield important information regarding its genetic architecture. And finally we review evidence from both complex and single-gene disorders, which provide insight into the molecular mechanisms underlying the genetic basis of human memory function.

Indexed as

Schizophrenic PsychologyAlzheimer DiseaseAnimalsBrainGenetic Association StudiesHeredityHumansIndividualityMemory, Long-TermModels, NeurologicalNeural PathwaysNeurofibromatosis 1Schizophrenia

Identifiers

PMID21832260
PMCPMC3545476

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.