Evidence map›Paper›PMID 21832101›Full record

ArticleClinical and vaccine immunology : CVI2011

Epithelial interleukin-8 responses to oral bacterial biofilms.

R Peyyala, S Kirakodu, K F Novak, J L Ebersole

Abstract read
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Differential Response of Oral Mucosal and Gingival Cells toFrontiers in cellular and infection microbiology · 2021
    Article
  2. Article
  3. Article
  4. Dynamic interactions of neutrophils and biofilms.Journal of oral microbiology · 2014
    Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

R PeyyalaCenter for Oral Health Research, College of Dentistry, University of Kentucky, 414 HSRB, 1095 VA Drive, Lexington, KY 40536, USA. rpeyy1@email.uky.edu
S Kirakodu
K F Novak
J L Ebersole

Funding

Analyses of Host-Biofilm Interactions: A Novel Polymicrobial ModelR21DE018177 · NIDCR · UNIVERSITY OF KENTUCKY · PI NOVAK, KAREN F. · 2008 to 2009
$403k
NIDCR NIH HHS R21 DE018177
6 · The paper itself

Abstract

An in vitro model of bacterial biofilms on rigid gas-permeable contact lenses (RGPLs) was developed to challenge oral epithelial cells. This novel model provided seminal data on oral biofilm-host cell interactions, and with selected bacteria, the biofilms were more effective than their planktonic counterparts at stimulating host cell responses.

Indexed as

BiofilmsBacteriaEpithelial CellsHost-Pathogen InteractionsInterleukin-8Mouth MucosaInterleukin-8

Identifiers

PMID21832101
PMCPMC3187022

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.