ArticleJournal of the Royal Society, Interface2012
The indentation of pressurized elastic shells: from polymeric capsules to yeast cells.
Article in Journal of the Royal Society, Interface, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 144 citations in OpenAlex.
- Surface mechanics and compressive stress impact mammalian follicle development.Nature communications · 2025Article
- Force spectroscopy reveals membrane fluctuations and surface adhesion of extracellular nanovesicles impact their elastic behavior.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- A look beyond topography: Transient phenomena ofScience advances · 2025Article
- Reversible bending of U-shaped plant petioles under dehydration.Quantitative plant biology · 2025Article
- Theoretical Studies on Assembly, Physical Stability, and Dynamics of Viruses.Sub-cellular biochemistry · 2024Review
- Review
- Ocular Deformations in Spaceflight-Associated Neuro-Ocular Syndrome and Idiopathic Intracranial Hypertension.Investigative ophthalmology & visual science · 2023Article
- The role of the cortex in indentation experiments of animal cells.Biomechanics and modeling in mechanobiology · 2023Article
- Bending stiffness ofLab on a chip · 2022Article
- Elastic shell theory for plant cell wall stiffness reveals contributions of cell wall elasticity and turgor pressure in AFM measurement.Scientific reports · 2022Article
- Macromolecular crowding limits growth under pressure.Nature physics · 2022Article
- Compression of a pressurized spherical shell by a spherical or flat probe.The European physical journal. E, Soft matter · 2022Article
- 3D mechanical characterization of single cells and small organisms using acoustic manipulation and force microscopy.Nature communications · 2021Article
- Validity of Winkler's mattress model for thin elastomeric layers: beyond Poisson's ratio.Proceedings. Mathematical, physical, and engineering sciences · 2020Article
- Correlating nuclear morphology and external force with combined atomic force microscopy and light sheet imaging separates roles of chromatin and lamin A/C in nuclear mechanics.Molecular biology of the cell · 2020Article
- Adenovirus major core protein condenses DNA in clusters and bundles, modulating genome release and capsid internal pressure.Nucleic acids research · 2019Article
- Article
- Viral nanomechanics with a virtual atomic force microscope.Journal of physics. Condensed matter : an Institute of Physics journal · 2018Article
- Finite indentation of highly curved elastic shells.Proceedings. Mathematical, physical, and engineering sciences · 2018Article
- Mechanics and Buckling of Biopolymeric Shells and Cell Nuclei.Biophysical journal · 2017Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pressurized elastic capsules arise at scales ranging from the 10 m diameter pressure vessels used to store propane at oil refineries to the microscopic polymeric capsules that may be used in drug delivery. Nature also makes extensive use of pressurized elastic capsules: plant cells, bacteria and fungi have stiff walls, which are subject to an internal turgor pressure. Here, we present theoretical, numerical and experimental investigations of the indentation of a linearly elastic shell subject to a constant internal pressure. We show that, unlike unpressurized shells, the relationship between force and displacement demonstrates two linear regimes. We determine analytical expressions for the effective stiffness in each of these regimes in terms of the material properties of the shell and the pressure difference. As a consequence, a single indentation experiment over a range of displacements may be used as a simple assay to determine both the internal pressure and elastic properties of capsules. Our results are relevant for determining the internal pressure in bacterial, fungal or plant cells. As an illustration of this, we apply our results to recent measurements of the stiffness of baker's yeast and infer from these experiments that the internal osmotic pressure of yeast cells may be regulated in response to changes in the osmotic pressure of the external medium.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.