ArticleBMC musculoskeletal disorders2011
Reference ranges for bone mineral density and prevalence of osteoporosis in Vietnamese men and women.
Article in BMC musculoskeletal disorders, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
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36 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Updated practice guideline for dual-energy X-ray absorptiometry (DXA).European journal of nuclear medicine and molecular imaging · 2025Guideline
- Prevalence of osteoporosis and incidence of related fractures in developed economies in the Asia Pacific region: a systematic review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023Pooled it
- Z-score discordance and contributing factors in healthy premenopausal women with low bone mineral density: the Korean National Health and Nutrition Examination Survey 2008-9.Journal of bone and mineral metabolism · 2016Trial
- Different reference BMDs affect the prevalence of osteoporosis.Journal of bone and mineral metabolism · 2016Trial
- 'Find Your Float': A Public Health Approach to Addressing Drowning Inequities in People of African, Caribbean and Asian Heritage: A Cross-Sectional Study.International journal of environmental research and public health · 2026Article
- Consensus statement on the application of artificial intelligence in osteoporosis screening and management: perspectives from the Asia-Pacific region.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Artificial intelligence-assisted screening reveals high prevalence of osteoporosis in Vietnamese adults using pelvic and hip radiographs.Osteoporosis and sarcopenia · 2026Article
- Muscle mass, not fat mass, predicts vertebral fracture risk: Vietnam osteoporosis study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Assessment of peak bone mineral density and its associated factors in Vietnamese adults: A cross-sectional study.PloS one · 2026Article
- Femoral bone mineral density reference values by sex and ethnicity: Findings from the Qatar Biobank study.Osteoporosis and sarcopenia · 2025Article
- A predictive nomogram for selective screening of asymptomatic vertebral fractures: The Vietnam Osteoporosis Study.Osteoporosis and sarcopenia · 2025Article
- Osteoporosis in men-East and West: Can the twain meet? A perspective from Asia.Osteoporosis and sarcopenia · 2024Review
- Prevalence, incidence of and risk factors for vertebral fracture in the community: the Vietnam Osteoporosis Study.Scientific reports · 2024Article
- Article
- Correlation between individual thigh muscle volume and grip strength in relation to sarcopenia with automated muscle segmentation.PloS one · 2024Article
- Osteoporosis: Molecular Pathology, Diagnostics, and Therapeutics.International journal of molecular sciences · 2023Review
- Longitudinal changes in bone mineral density during perimenopausal transition: the Vietnam Osteoporosis Study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023Article
- Low bone mineral density and its related factors in adults with congenital heart disease in Vietnam: A cross-sectional study.Health science reports · 2022Article
- Current Status of the Diagnosis and Management of Osteoporosis.International journal of molecular sciences · 2022Review
- Reference values for bone density and bone mineral content from 5 to 80 years old in a province of Chile.PeerJ · 2022Article
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5 authors.
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Abstract
backgroundThe aim of this study was to examine the effect of different reference ranges in bone mineral density on the diagnosis of osteoporosis.
methodsThis cross-sectional study involved 357 men and 870 women aged between 18 and 89 years, who were randomly sampled from various districts within Ho Chi Minh City, Vietnam. BMD at the femoral neck, lumbar spine and whole body was measured by DXA (Hologic QDR4500). Polynomial regression models and bootstraps method were used to determine peak BMD and standard deviation (SD). Based on the two parameters, we computed T-scores (denoted by TVN) for each individual in the study. A similar diagnosis was also done based on T-scores provided by the densitometer (TDXA), which is based on the US White population (NHANES III). We then compared the concordance between TVN and TDXA in the classification of osteoporosis. Osteoporosis was defined according to the World Health Organization criteria.
resultsIn post-menopausal women, the prevalence of osteoporosis based on femoral neck TVN was 29%, but when the diagnosis was based on TDXA, the prevalence was 44%. In men aged 50+ years, the TVN-based prevalence of osteoporosis was 10%, which was lower than TDXA-based prevalence (30%). Among 177 women who were diagnosed with osteoporosis by TDXA, 35% were actually osteopenia by TVN. The kappa-statistic was 0.54 for women and 0.41 for men.
conclusionThese data suggest that the T-scores provided by the Hologic QDR4500 over-diagnosed osteoporosis in Vietnamese men and women. This over-diagnosis could lead to over-treatment and influence the decision of recruitment of participants in clinical trials.
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