Evidence map›Paper›PMID 21830102›Full record

ReviewCurrent atherosclerosis reports2011

Genetic testing for early detection of individuals at risk of coronary heart disease and monitoring response to therapy: challenges and promises.

H Robert Superko, Robert Roberts, Arthur Agatston, Stephen Frohwein, Jason S Reingold, Thomas J White, John J Sninsky, Basil Margolis, Kathryn M Momary, Brenda C Garrett and 1 more

Open access · hybridAbstract readReview
In one paragraph

Review in Current atherosclerosis reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Coronary heart disease in young adults.Current atherosclerosis reports · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

H Robert SuperkoCelera Corporation, 1401 Harbor Bay Parkway, Alameda, CA 94502, USA. HighHDL@mac.com
Robert Roberts
Arthur Agatston
Stephen Frohwein
Jason S Reingold
Thomas J White
John J Sninsky
Basil Margolis
Kathryn M Momary
Brenda C Garrett
Spencer B King
Saint Joseph's Hospital · USAlameda Applied Sciences Corporation (United States) · USEmory University · USUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary heart disease (CHD) often presents suddenly with little warning. Traditional risk factors are inadequate to identify the asymptomatic high-risk individuals. Early identification of patients with subclinical coronary artery disease using noninvasive imaging modalities would allow the early adoption of aggressive preventative interventions. Currently, it is impractical to screen the entire population with noninvasive coronary imaging tools. The use of relatively simple and inexpensive genetic markers of increased CHD risk can identify a population subgroup in which benefit of atherosclerotic imaging modalities would be increased despite nominal cost and radiation exposure. Additionally, genetic markers are fixed and need only be measured once in a patient's lifetime, can help guide therapy selection, and may be of utility in family counseling.

Indexed as

Genetic TestingAllelesCoronary DiseaseDiagnostic ImagingEarly DiagnosisGenotypeHumansMass ScreeningPhenotypePolymorphism, GeneticPredictive Value of TestsRisk AssessmentRisk Factors

Identifiers

PMID21830102
PMCPMC3165136
OpenAlexW2058080542

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.