ArticlePloS one2011
Comparative analysis of Korean human gut microbiota by barcoded pyrosequencing.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers.
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Who cites it
119 citing papers in PubMed, 227 citations in OpenAlex.
- Trial
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- Safety, Tolerability, and Gut Microbiota Impact of Sericin-Derived Oligopeptides (SDOs) from Yellow Silk Cocoons in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.Foods (Basel, Switzerland) · 2026Article
- Quantitative evaluation of microbiome sequencing resolution under varying experimental conditions using defined mock communities.Scientific reports · 2026Article
- Species-level taxonomic characterization enhances the power of saliva and feces stain microbiota for inferring the time since deposition (TsD).International journal of legal medicine · 2026Article
- Results from the IceGut study: tracking the gut microbiome development from mothers and infants up to five years of age.mSphere · 2025Article
- Healthy human gut microbiome: Towards standardized research.AIMS microbiology · 2025Review
- Changes in the intestinal microbiota of Japanese children during the first 3.5 years of life.Scientific reports · 2024Article
- The role of host traits and geography in shaping the gut microbiome of insectivorous bats.mSphere · 2024Article
- How Different Are the Influences of Mediterranean and Japanese Diets on the Gut Microbiome?Endocrine, metabolic & immune disorders drug targets · 2024Review
- Microbiota, natural products, and human health: exploring interactions for therapeutic insights.Frontiers in cellular and infection microbiology · 2024Review
- Gut Phageome-An Insight into the Role and Impact of Gut Microbiome and Their Correlation with Mammal Health and Diseases.Microorganisms · 2023Review
- Lifestyle patterns influence the composition of the gut microbiome in a healthy Chinese population.Scientific reports · 2023Article
- Mechanistic Insights into Immune-Microbiota Interactions and Preventive Role of Probiotics Against Autoimmune Diabetes Mellitus.Probiotics and antimicrobial proteins · 2023Review
- Review
- Gut microbiota characteristics of Mongolian and Han populations in anti-tuberculosis drug-induced liver injury: a population-based case-control study.BMC microbiology · 2023Article
- Gut microbiota in SLE: from animal models to clinical evidence and pharmacological perspectives.Lupus science & medicine · 2023Review
- Analysis of gut bacteriome ofFrontiers in microbiology · 2023Article
- Designation of optimal reference strains representing the infant gut bifidobacterial species through a comprehensive multi-omics approach.Environmental microbiology · 2022Article
- Characteristics of the Gut Bacterial Composition in People of Different Nationalities and Religions.Microorganisms · 2022Review
59 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human gut microbiota plays important roles in harvesting energy from the diet, stimulating the proliferation of the intestinal epithelium, developing the immune system, and regulating fat storage in the host. Characterization of gut microbiota, however, has been limited to western people and is not sufficiently extensive to fully describe microbial communities. In this study, we investigated the overall composition of the gut microbiota and its host specificity and temporal stability in 20 Koreans using 454-pyrosequencing with barcoded primers targeting the V1 to V3 region of the bacterial 16S rRNA gene. A total of 303,402 high quality reads covered each sample and 8,427 reads were analyzed on average. The results were compared with those of individuals from the USA, China and Japan. In general, microbial communities were dominated by five previously identified phyla: Actinobacteria, Firmicutes, Bacteroidetes, Fusobacteria, and Proteobacteria. UPGMA cluster analysis showed that the species composition of gut microbiota was host-specific and stable over the duration of the test period, but the relative abundance of each member fluctuated. 43 core Korean gut microbiota were identified by comparison of sequences from each individual, of which 15 species level phylotypes were related to previously-reported butyrate-producing bacteria. UniFrac analysis revealed that human gut microbiota differed between countries: Korea, USA, Japan and China, but tended to vary less between individual Koreans, suggesting that gut microbial composition is related to internal and external characteristics of each country member such as host genetics and diet styles.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.