ArticleCurrent diabetes reports2011
Immunoisolation of pancreatic islet grafts with no recipient's immunosuppression: actual and future perspectives.
Article in Current diabetes reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Conformal encapsulation of mammalian stem cells using modified hyaluronic acid.Journal of materials chemistry. B · 2024Article
- Immunoisolation of murine islet allografts in vascularized sites through conformal coating with polyethylene glycol.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2018Article
- Article
- Effects of Composition of Alginate-Polyethylene Glycol Microcapsules and Transplant Site on Encapsulated Islet Graft Outcomes in Mice.Transplantation · 2017Article
- Article
- Re-engineering islet cell transplantation.Pharmacological research · 2015Review
- Development of an encapsulated stem cell-based therapy for diabetes.Expert opinion on biological therapy · 2015Review
- Insights in Behavior of Variably Formulated Alginate-Based Microcapsules for Cell Transplantation.BioMed research international · 2015Article
- Device design and materials optimization of conformal coating for islets of Langerhans.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Membranes to achieve immunoprotection of transplanted islets.Frontiers in bioscience (Landmark edition) · 2014Review
- Microfluidic array with integrated oxygenation control for real-time live-cell imaging: effect of hypoxia on physiology of microencapsulated pancreatic islets.Analytical chemistry · 2013Article
- Core-shell hydrogel microcapsules for improved islets encapsulation.Advanced healthcare materials · 2013Article
- 25 YEARS OF THE RICORDI AUTOMATED METHOD FOR ISLET ISOLATION.CellR4-- repair, replacement, regeneration, & reprogramming · 2013Article
- Concise review: pancreas regeneration: recent advances and perspectives.Stem cells translational medicine · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In spite of steady and remarkable progress, islet transplantation in patients with type 1 diabetes mellitus (T1DM) continues to face two major bottlenecks: inadequate availability of human pancreatic donors and necessity to totally immunosuppress the graft recipients lifelong. Microencapsulation of the islet grafts within highly biocompatible and selective permeable biomembranes could obviate use of the immunosuppressants, while potentially offering the opportunity to use a wide array of insulin-producing cells, in active development, including xenogeneic pig islets. Although macrodevices and microcapsules, which essentially differ by size/configuration, and both serve for immunoisolation devices, have been used for many years with initial human applications, new products on development in both areas might open new perspectives for more focused use in patients with T1DM. Physical-chemical properties and material engineering of these devices are critically reviewed to assess where we actually stand and where the future expansion of these technologies may go.
Indexed as
Identifiers
21826429What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.