Evidence map›Paper›PMID 21826228›Full record

ArticlePloS one2011

Towards a characterization of behavior-disease models.

Nicola Perra, Duygu Balcan, Bruno Gonçalves, Alessandro Vespignani

Abstract read
In one paragraph

Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Comparative evaluation of behavioral epidemic models using COVID-19 data.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  19. The impact of threshold decision mechanisms of collective behavior on disease spread.Proceedings of the National Academy of Sciences of the United States of America · 2023
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34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nicola PerraCenter for Complex Networks and Systems Research, School of Informatics and Computing, Indiana University, Bloomington, Indiana, United States of America. nperra@indiana.edu
Duygu Balcan
Bruno Gonçalves
Alessandro Vespignani

Funding

EpiC: A Cyberinfrastructure that Supports the Plug-and-Play of Datasets & AlgoriR21DA024259 · NIDA · TRUSTEES OF INDIANA UNIVERSITY · PI BORNER, KATY, SHERMAN, STEVEN J · 2007 to 2010
$1.2M
NIDA NIH HHS R21 DA024259NIDA NIH HHS R21-DA024259
6 · The paper itself

Abstract

The last decade saw the advent of increasingly realistic epidemic models that leverage on the availability of highly detailed census and human mobility data. Data-driven models aim at a granularity down to the level of households or single individuals. However, relatively little systematic work has been done to provide coupled behavior-disease models able to close the feedback loop between behavioral changes triggered in the population by an individual's perception of the disease spread and the actual disease spread itself. While models lacking this coupling can be extremely successful in mild epidemics, they obviously will be of limited use in situations where social disruption or behavioral alterations are induced in the population by knowledge of the disease. Here we propose a characterization of a set of prototypical mechanisms for self-initiated social distancing induced by local and non-local prevalence-based information available to individuals in the population. We characterize the effects of these mechanisms in the framework of a compartmental scheme that enlarges the basic SIR model by considering separate behavioral classes within the population. The transition of individuals in/out of behavioral classes is coupled with the spreading of the disease and provides a rich phase space with multiple epidemic peaks and tipping points. The class of models presented here can be used in the case of data-driven computational approaches to analyze scenarios of social adaptation and behavioral change.

Indexed as

Disease OutbreaksModels, TheoreticalHumans

Identifiers

PMID21826228
PMCPMC3149628

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.