ArticlePloS one2011
Proteomic characterization of cellular and molecular processes that enable the Nanoarchaeum equitans--Ignicoccus hospitalis relationship.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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40 citing papers in PubMed.
- Mono-mix strategy enables comparative proteomics of a cross-kingdom microbial symbiosis.PloS one · 2026Article
- Cooperation and Competition Were Primary Driving Forces for Biological Evolution.Microbial physiology · 2025Review
- Cell surface architecture of the cultivated DPANN archaeonJournal of bacteriology · 2024Article
- Genesis of ectosymbiotic features based on commensalistic syntrophy.Scientific reports · 2024Article
- Article
- The monomeric archaeal primase from Nanoarchaeum equitans harbours the features of heterodimeric archaeoeukaryotic primases and primes sequence-specifically.Nucleic acids research · 2023Article
- Culture-based approaches to studying "microbial dark matter".Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- A Micrarchaeon Isolate Is Covered by a Proteinaceous S-Layer.Applied and environmental microbiology · 2022Article
- Functional compartmentalization and metabolic separation in a prokaryotic cell.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- A promiscuous ancestral enzyme´s structure unveils protein variable regions of the highly diverse metallo-β-lactamase family.Communications biology · 2021Article
- An archaeal symbiont-host association from the deep terrestrial subsurface.The ISME journal · 2019Article
- Igni18, a novel metallo-hydrolase from the hyperthermophilic archaeon Ignicoccus hospitalis KIN4/I: cloning, expression, purification and X-ray analysis.Acta crystallographica. Section F, Structural biology communications · 2019Article
- Purification of a Crenarchaeal ATP Synthase in the Light of the Unique Bioenergetics ofJournal of bacteriology · 2019Article
- Genomic diversity, lifestyles and evolutionary origins of DPANN archaea.FEMS microbiology letters · 2019Review
- Single-cell genomics of co-sorted Nanoarchaeota suggests novel putative host associations and diversification of proteins involved in symbiosis.Microbiome · 2018Article
- An Escherichia coli Nitrogen Starvation Response Is Important for Mutualistic Coexistence with Rhodopseudomonas palustris.Applied and environmental microbiology · 2018Article
- Label-Free Proteomics of a Defined, Binary Co-culture Reveals Diversity of Competitive Responses Between Members of a Model Soil Microbial System.Microbial ecology · 2018Article
- Article
- Multi-omics analysis provides insight to the Ignicoccus hospitalis-Nanoarchaeum equitans association.Biochimica et biophysica acta. General subjects · 2017Article
- Bypassing rRNA methylation by RsmA/Dim1during ribosome maturation in the hyperthermophilic archaeon Nanoarchaeum equitans.Nucleic acids research · 2017Article
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9 authors.
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Abstract
Nanoarchaeum equitans, the only cultured representative of the Nanoarchaeota, is dependent on direct physical contact with its host, the hyperthermophile Ignicoccus hospitalis. The molecular mechanisms that enable this relationship are unknown. Using whole-cell proteomics, differences in the relative abundance of >75% of predicted protein-coding genes from both Archaea were measured to identify the specific response of I. hospitalis to the presence of N. equitans on its surface. A purified N. equitans sample was also analyzed for evidence of interspecies protein transfer. The depth of cellular proteome coverage achieved here is amongst the highest reported for any organism. Based on changes in the proteome under the specific conditions of this study, I. hospitalis reacts to N. equitans by curtailing genetic information processing (replication, transcription) in lieu of intensifying its energetic, protein processing and cellular membrane functions. We found no evidence of significant Ignicoccus biosynthetic enzymes being transported to N. equitans. These results suggest that, under laboratory conditions, N. equitans diverts some of its host's metabolism and cell cycle control to compensate for its own metabolic shortcomings, thus appearing to be entirely dependent on small, transferable metabolites and energetic precursors from I. hospitalis.
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