ArticleThorax2011
Urbanisation is associated with prevalence of childhood asthma in diverse, small rural communities in Ecuador.
Article in Thorax, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.
- Pooled it
- Features of asthma which provide meaningful insights for understanding the disease heterogeneity.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2018Trial
- Role of exhaled nitric oxide as a predictor of atopy.Respiratory research · 2013Trial
- Maternal consumption of urbanized diet compromises early-life health in association with gut microbiota.Gut microbes · 2025Review
- Rurality and relative poverty drive acquisition of a stable and diverse gut microbiome in early childhood in a non-industrialized setting.Scientific reports · 2025Article
- Rurality and relative poverty drive acquisition of a stable and diverse gut microbiome in early childhood in a non-industrialized setting.Research square · 2024Article
- Social inequalities in childhood asthma.The World Allergy Organization journal · 2024Review
- Cardiometabolic diseases and associated risk factors in transitional rural communities in tropical coastal Ecuador.PloS one · 2024Article
- Guideline Implementation for Improved Asthma Management and Treatment Adherence in Children in Jordan.Healthcare (Basel, Switzerland) · 2023Article
- Influence of Farm Environment on Asthma during the Life Course: A Population-Based Birth Cohort Study in Northern Finland.International journal of environmental research and public health · 2023Article
- Global Considerations in Asthma Treatment: Management in Low Resource Settings.Advances in experimental medicine and biology · 2023Article
- Anxiety disorders and asthma among adolescents in Uganda: role of early-life exposures.ERJ open research · 2021Article
- Cesarean section and risk of allergies in Ecuadorian children: A cross-sectional study.Immunity, inflammation and disease · 2020Article
- Developmental Origins of Health and Disease: Impact of environmental dust exposure in modulating microbiome and its association with non-communicable diseases.Journal of developmental origins of health and disease · 2020Review
- Measuring urbanicity as a risk factor for childhood wheeze in a transitional area of coastal ecuador: a cross-sectional analysis.BMJ open respiratory research · 2020Article
- A hybrid of two major Blomia tropicalis allergens as an allergy vaccine candidate.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2020Article
- Environmental exposures and mechanisms in allergy and asthma development.The Journal of clinical investigation · 2019Review
- Allergic Diseases and Atopy Among Schoolchildren in Eastern Croatia.Acta clinica Croatica · 2018Article
- Allergy-related disorders (ARDs) among Ethiopian primary school-aged children: Prevalence and associated risk factors.PloS one · 2018Article
- The association between local meteorological changes and exacerbation of acute wheezing in Kandy, Sri Lanka.Global health action · 2018Article
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundStudies conducted in transitional communities from Africa and Asia have pointed to the process of urbanisation as being responsible for the increase in asthma prevalence in developing regions. In Latin America, there are few published data available on the potential impact of urbanisation on asthma prevalence. The aim of the present study was to explore how the process of urbanisation may explain differences in asthma prevalence in transitional communities in north-eastern Ecuador. METHODOLOGY/PRINCIPAL
findingsAn ecological study was conducted in 59 communities in Esmeraldas Province, Ecuador. Indicators of urbanisation were grouped into three indices representing the processes associated with urbanisation: socioeconomic, lifestyle and urban infrastructure. Categorical principal components analysis was used to generate scores for each index and a fourth index--a summary urbanisation index--was derived from the most representative variables in each of the three indices. The authors analysed the associations between community asthma prevalence and the indices, as well as with each indicator variable of every group. The overall prevalence of asthma was 10.1% (range 0-31.4% between communities). Three of the four indices presented significant associations with community asthma prevalence: socioeconomic (r = 0.295, p = 0.023), lifestyle (r = 0.342, p = 0.008) and summary urbanisation index (r = 0.355, p = 0.006). Variables reflecting better socioeconomic status and a more urban lifestyle were associated with greater asthma prevalence.
conclusionsThese data provide evidence that the prevalence of asthma increases with increasing levels of urbanisation in transitional communities, and factors associated with greater socioeconomic level and changes towards a more urban lifestyle may be particularly important.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.