Trial reportNeuro-oncology2011
Neurocytomas: long-term experience of a single institution.
Trial report in Neuro-oncology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 61 citations in OpenAlex.
- Long term outcomes and predictors of recurrence in central neurocytomas: a 35-year multi-institutional experience.Journal of neuro-oncology · 2026Article
- The clinical spectrum of central neurocytomas ranges from benign to leptomeningeal disseminating disease: a single institutional surgical series of 33 patients.Frontiers in surgery · 2025Article
- Central Neurocytoma in a Teenager, a Rare Cause of Hemiplegia, and a Diagnostic Dilemma in a Resource-Poor Setting.Case reports in pathology · 2024Article
- The role of methylation profiling in histologically diagnosed neurocytoma: a case series.Journal of neuro-oncology · 2022Article
- Clinical Outcomes and Prognostic Analysis of 101 Patients of Central Neurocytoma: A 10-Year Treatment Experience at a Single Institution.Frontiers in oncology · 2022Article
- Impact of Adjuvant Radiotherapy in Patients with Central Neurocytoma: A Multicentric International Analysis.Cancers · 2021Article
- The last decade's experience of management of central neurocytomas: Treatment strategies and new options.Surgical neurology international · 2021Article
- Clinical Outcome After Microsurgical Resection of Central Neurocytoma: A Single-Centre Analysis of 15 Years.Frontiers in neurology · 2021Article
- Intraventricular neuroepithelial tumors: surgical outcome, technical considerations and review of literature.BMC cancer · 2020Observational
- Long-term follow-up of lateral ventricular central neurocytoma treated with subtotal resection followed by concurrent chemoradiotherapy and add on chemotherapy - Case report from a Tertiary Kenyan Cancer Hospital.Surgical neurology international · 2020Article
- Individual Treatment Decisions for Central Neurocytoma.Frontiers in neurology · 2020Article
- The role of chemotherapy in the treatment of central neurocytoma.CNS oncology · 2019Review
- The epidemiology of central and extraventricular neurocytoma in the United States between 2006 and 2014.Journal of neuro-oncology · 2019Article
- Prognosis and treatment outcomes of central neurocytomas: clinical interrogation based on a single center experience.Journal of neuro-oncology · 2018Article
- Article
- Clinical outcome and prognostic factors for central neurocytoma: twenty year institutional experience.Journal of neuro-oncology · 2016Article
- A comparative study of intraventricular central neurocytomas and extraventricular neurocytomas.Journal of neuro-oncology · 2015Article
- Treatment strategies for huge central neurocytomas.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2015Article
- Long-term outcomes of adjuvant radiotherapy after surgical resection of central neurocytoma.Radiation oncology (London, England) · 2014Article
- Two cases of intraventricular hemorrhage in young patients.Brain pathology (Zurich, Switzerland) · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a lack of studies reporting on outcomes of control and treatment toxicities for neurocytomas. A 25-year retrospective review of a tertiary center's experience with neurocytomas was completed to report on these outcomes. All cerebral neurocytoma cases (19 patients; median age, 31 years; range, 18-62 years; 18 intraventricular and 1 extraventricular) treated between 1984 and 2009 were analyzed, including central pathology and radiology reviews. Median follow-up was 104.5 months (range, 0.75-261.7 months). Primary treatment was surgery alone (n = 18 patients), followed by surgery and adjuvant radiotherapy (n = 1). The crude local control rate after surgery was 68% for all cases (cerebral neurocytomas) and 74% for central neurocytomas. Salvage therapies included further surgery (n = 4), radiation (n = 3), and chemotherapy (n = 1). Ten-year Kaplan-Meier overall and relapse-free survival rates were 82% and 62% and 81% and 57%, respectively, for all cases and for central neurocytomas only. The median overall survival and relapse-free survival were 104.5 and 79.3 months, respectively, for all cases and for central neurocytomas. Ten patients had grade 3/4 toxicity, and 1 patient had a grade 5 perioperative hemorrhage that resulted in death 23 days after surgery. Late grade 3/4 toxicities occurred in 9 patients. Three patients had permanent grade 2 motor or cognitive deficits. We provide the first report outlining toxicities and survival outcomes in a series of 19 patients. Our experience suggests that initial surgery provides durable local control rates in two-thirds of patients, with low risk for significant permanent deficits. Salvage therapy with surgery and/or radiation provides durable local control in tumors that recur after surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.