Evidence map›Paper›PMID 21824883›Full record

ArticlePediatrics2011

Suicidal behavior differs among early and late adolescents treated with antidepressant agents.

Erik B Hysinger, S Todd Callahan, T Lynne Caples, D Catherine Fuchs, Richard Shelton, William O Cooper

Abstract read
In one paragraph

Article in Pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Erik B HysingerDivision of General Pediatrics, Department of Pediatrics, Vanderbilt School of Medicine, Nashville, Tennessee, USA.
S Todd Callahan
T Lynne Caples
D Catherine Fuchs
Richard Shelton
William O Cooper

Funding

Suicidality Associated with Antidepressants inTennCare Children and AdolescentsR01MH079903 · NIMH · VANDERBILT UNIVERSITY · PI COOPER, WILLIAM O. · 2008 to 2011
$1.4M
NIMH NIH HHS 5R01MH079903-03NIMH NIH HHS R01 MH079903
6 · The paper itself

Abstract

objectiveTo identify circumstances and characteristics of suicidal behavior among early (aged 10-14 years) and late (aged 15-18 years) adolescents from a cohort of youth who were prescribed antidepressant medication.

methodsIn-depth reviews of all available medical records were performed for 250 randomly chosen confirmed episodes of suicidal behavior identified as part of a large retrospective cohort study of antidepressant users and suicidal behavior. Study data were obtained from Tennessee Medicaid records and death certificates from January 1, 1995, to December 31, 2006. Medical records and autopsy reports for cases identified from electronic data were adjudicated by 2 investigators blinded to exposure status and classified by using a validated scale.

resultsOf the 250 cases reviewed, 65.6% were female and 26.4% were aged 10 to 14 years. Medication ingestion was the most frequent method of suicidal behavior for both early and late adolescents; however, early adolescents were significantly more likely to use hanging as a method of suicide. Nearly one-half of the adolescents had previously attempted suicide. Early adolescents were significantly more likely to have a history of sexual abuse and significantly less likely to have a history of substance abuse. Early adolescents were also significantly more likely than older adolescents to have a history of a psychotic disorder and to report hallucinations before the suicide attempt.

conclusionSuicidal behavior among early and late adolescents prescribed antidepressant medication differed in terms of methods used, previous psychiatric history, and proximal symptoms.

Indexed as

AdolescentAntidepressive AgentsChildDepressionFemaleHumansInterpersonal RelationsMaleMedicaidRisk AssessmentSuicidal IdeationSuicideSuicide, AttemptedSuicide PreventionTennesseeUnited StatesAntidepressive Agents

Identifiers

PMID21824883
PMCPMC3387879

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.