Evidence map›Paper›PMID 21824730›Full record

ReviewVeterinary parasitology2011

Population genetics of Toxoplasma gondii: new perspectives from parasite genotypes in wildlife.

Jered M Wendte, Amanda K Gibson, Michael E Grigg

Abstract readReview
In one paragraph

Review in Veterinary parasitology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
8.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Isolation, genotyping and phenotypingFood and waterborne parasitology · 2025
    Review
  5. Exposure of Eurasian blackbird (International journal for parasitology. Parasites and wildlife · 2025
    Article
  6. Molecular detection and characterisation ofInternational journal for parasitology. Parasites and wildlife · 2025
    Article
  7. Article
  8. Exploring the epidemiological role of the Eurasian lynx (International journal for parasitology. Parasites and wildlife · 2023
    Article
  9. Article
  10. Prevalence and genetic characterization ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023
    Article
  11. Fatal toxoplasmosis in Little Penguins (Eudyptula minor) from Penguin Island, Western Australia.International journal for parasitology. Parasites and wildlife · 2022
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Diversity ofFood and waterborne parasitology · 2019
    Review
  17. Review
  18. Human impact on the diversity and virulence of the ubiquitous zoonotic parasiteProceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jered M WendteMolecular Parasitology Unit, Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-0425, USA.
Amanda K Gibson
Michael E Grigg
National Institutes of Health · USOklahoma State University · US

Funding

Toxoplasma Population GeneticsZIAAI001018 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI GRIGG, MICHAEL · 2009 to 2025
$11.3M
Toxoplasma Population GeneticsZ01AI001018 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI GRIGG, MICHAEL · 2007 to 2008
$801k
Intramural NIH HHS Z01 AI001018Intramural NIH HHS ZIA AI001018
6 · The paper itself

Abstract

Toxoplasma gondii, a zoonotic protozoal parasite, is well-known for its global distribution and its ability to infect virtually all warm-blooded vertebrates. Nonetheless, attempts to describe the population structure of T. gondii have been primarily limited to samples isolated from humans and domesticated animals. More recent studies, however, have made efforts to characterize T. gondii isolates from a wider range of host species and geographic locales. These findings have dramatically changed our perception of the extent of genetic diversity in T. gondii and the relative roles of sexual recombination and clonal propagation in the parasite's lifecycle. In particular, identification of novel, disease-causing T. gondii strains in wildlife has raised concerns from both a conservation and public health perspective as to whether distinct domestic and sylvatic parasite gene pools exist. If so, overlap of these cycles may represent regions of high probability of disease emergence. Here, we attempt to answer these key questions by reviewing recent studies of T. gondii infections in wildlife, highlighting those which have advanced our understanding of the genetic diversity and population biology of this important zoonotic pathogen.

Indexed as

AnimalsAnimals, WildDNA, ProtozoanGenetic VariationGenotypeHumansPhylogenyPolymerase Chain ReactionPolymorphism, Restriction Fragment LengthToxoplasmaToxoplasmosis, AnimalZoonosesDNA, Protozoan

Identifiers

PMID21824730
PMCPMC3430134
OpenAlexW2168130949

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.