Evidence map›Paper›PMID 21823044›Full record

ArticleClinical and experimental nephrology2011

Induction of remission following a single dose of rituximab alone in a patient with minimal change nephrotic syndrome.

Nobuyuki Amemiya, Takashi Takei, Chiari Kojima, Hirohiko Nokiba, Mitsuyo Itabashi, Kosaku Nitta

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Clinical and experimental nephrology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nobuyuki AmemiyaDepartment of Medicine, Kidney Center, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
Takashi Takei
Chiari Kojima
Hirohiko Nokiba
Mitsuyo Itabashi
Kosaku Nitta
Tokyo Women's Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment with a single dose of rituximab alone induced remission in a patient with relapsed minimal change nephrotic syndrome (MCNS). A 27-year-old man was given corticosteroid (prednisolone; PSL) and cyclosporine (CyA) therapy combined with rituximab for his fifth relapse in 2008. Thereafter, complete remission was achieved and maintained despite eventual discontinuation of the PSL and CyA. In 2010, we treated his sixth relapse with a single dose of rituximab. Complete remission was obtained 32 days later. This is the first report of rituximab monotherapy in the treatment of MCNS.

Indexed as

Adrenal Cortex HormonesAdultAntibodies, Monoclonal, Murine-DerivedCyclosporineHumansImmunologic FactorsImmunosuppressive AgentsMaleNephrosis, LipoidPrednisoloneRecurrenceRemission InductionRituximabTime FactorsTreatment OutcomeAdrenal Cortex HormonesAntibodies, Monoclonal, Murine-DerivedCyclosporineImmunologic FactorsImmunosuppressive AgentsPrednisoloneRituximab

Identifiers

PMID21823044
OpenAlexW2088812049

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.