ArticleClinical interventions in aging2011
Radio electric asymmetric brain stimulation in the treatment of behavioral and psychiatric symptoms in Alzheimer disease.
Article in Clinical interventions in aging, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 32 citations in OpenAlex.
- A Clinical Trial of Transcranial Electromagnetic Treatment in Alzheimer's Disease: Cognitive Enhancement and Associated Changes in Cerebrospinal Fluid, Blood, and Brain Imaging.Journal of Alzheimer's disease : JAD · 2019Trial
- Long-lasting changes in brain activation induced by a single REAC technology pulse in Wi-Fi bands. Randomized double-blind fMRI qualitative study.Scientific reports · 2014Trial
- Stress-related psycho-physiological disorders: randomized single blind placebo controlled naturalistic study of psychometric evaluation using a radio electric asymmetric treatment.Health and quality of life outcomes · 2011Trial
- REAC Neurobiological Modulation as a Precision Medicine Treatment for Fibromyalgia.Journal of personalized medicine · 2023Article
- Effects of the radio electric asymmetric conveyer (REAC) on motor disorders: An integrative review.Frontiers in medical technology · 2023Review
- A Scoping Review of Neuromodulation Techniques in Neurodegenerative Diseases: A Useful Tool for Clinical Practice?Medicina (Kaunas, Lithuania) · 2021Article
- Radio electric asymmetric conveyer neuromodulation in depression, anxiety, and stress.Neuropsychiatric disease and treatment · 2019Article
- Memory Prosthesis: Is It Time for a Deep Neuromimetic Computing Approach?Frontiers in neuroscience · 2019Article
- Radio Electric Asymmetric Conveyer Technology Modulates Neuroinflammation in a Mouse Model of Neurodegeneration.Neuroscience bulletin · 2018Article
- REAC neuromodulation treatments in subjects with severe socioeconomic and cultural hardship in the Brazilian state of Pará: a family observational pilot study.Neuropsychiatric disease and treatment · 2018Article
- REAC technology modifies pathological neuroinflammation and motor behaviour in an Alzheimer's disease mouse model.Scientific reports · 2016Article
- Brain stimulation for combating Alzheimer's disease.Frontiers in neurology · 2014Review
- Successful therapies for Alzheimer's disease: why so many in animal models and none in humans?Frontiers in pharmacology · 2014Review
- Preliminary pilot fMRI study of neuropostural optimization with a noninvasive asymmetric radioelectric brain stimulation protocol in functional dysmetria.Neuropsychiatric disease and treatment · 2012Article
- Neuropsychophysical optimization by REAC technology in the treatment of: sense of stress and confusion. Psychometric evaluation in a randomized, single blind, sham-controlled naturalistic study.Patient preference and adherence · 2012Article
- Noninvasive radioelectric asymmetric conveyor brain stimulation treatment improves balance in individuals over 65 suffering from neurological diseases: pilot study.Therapeutics and clinical risk management · 2012Article
- Regenerative treatment using a radioelectric asymmetric conveyor as a novel tool in antiaging medicine: an in vitro beta-galactosidase study.Clinical interventions in aging · 2012Article
- Radioelectric asymmetric stimulation of tissues as treatment for post-traumatic injury symptoms.International journal of general medicine · 2011Article
- Social anxiety disorder: radio electric asymmetric conveyor brain stimulation versus sertraline.Patient preference and adherence · 2011Article
- Radio electric tissue optimization in the treatment of surgical wounds.Clinical, cosmetic and investigational dermatology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeBehavioral and psychiatric symptoms of dementia (BPSD) are common in Alzheimer's disease (AD) and disrupt the effective management of AD patients. The present study explores the use of radio electric asymmetric brain stimulation (REAC) in patients who have had a poor response to pharmacological treatment. PATIENTS AND
methodsEight patients (five females and three males; mean [±standard deviation] age at study baseline: 69.9 ± 3.0 years) diagnosed with AD according to the DSM-IV-TR criteria (mean onset age of AD: 65.4 ± 3.5 years) were cognitively and psychometrically assessed with the Mini-Mental State Examination (MMSE), the Activity of Daily Living (ADL), the Instrumental Activity of Daily Living (IADL), and the Neuropsychiatric Inventory (NPI), prior to and after each of 2 REAC treatment cycles.
resultsScores on the MMSE and all subscales of the NPI (frequency, severity, and distress), the ADL, and the IADL were significantly improved following the initial REAC treatment. There was further significant improvement in all measurements (with a tendency for improvement in the IADL) after the second REAC treatment cycle.
conclusionThe improvement of cognitive and behavioral/psychiatric functioning following REAC treatment suggests that this innovative approach may be an effective, safe, and tolerable alternative to pharmacological treatment of AD patients, especially in the area of BPSD. Elderly patients suffering from other types of dementia may also benefit from REAC treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.