Evidence map›Paper›PMID 21822024›Full record

ArticleNeuroepidemiology2011

Racial and geographic differences in prevalence, awareness, treatment and control of dyslipidemia: the reasons for geographic and racial differences in stroke (REGARDS) study.

Richard M Zweifler, Leslie A McClure, Virginia J Howard, Mary Cushman, Martha K Hovater, Monika M Safford, George Howard, David C Goff

Abstract read
In one paragraph

Article in Neuroepidemiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  17. Ancestry, Telomere Length, and Atherosclerosis Risk.Circulation. Cardiovascular genetics · 2017
    Review
  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Richard M ZweiflerDivision of Neurology, Sentara Medical Group and Department of Neurology, Eastern Virginia Medical School, Norfolk, VA 23507, USA. rmzweifl@sentara.com
Leslie A McClure
Virginia J Howard
Mary Cushman
Martha K Hovater
Monika M Safford
George Howard
David C Goff

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
REGARDS - MI StudyR01HL080477 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LEVITAN, EMILY B, SAFFORD, MONIKA M · 2006 to 2020
$11.6M
NHLBI NIH HHS R01 HL080477NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

BACKGROUND/

aimsThere are racial and geographic disparities in stroke mortality, with higher rates among African Americans (AAs) and those living in the southeastern US ('stroke belt'). Racial and geographic differences in dyslipidemia prevalence, awareness, treatment and control may, in part, account for the observed disparities in stroke mortality.

methodsReasons for Geographic and Racial Differences in Stroke (REGARDS) is a national observational study of community-dwelling black and white participants aged 45 and older, with oversampling from the stroke belt. As of January 15, 2007, 26,122 participants were enrolled and a fasting lipid panel was available of 21,068. Awareness, treatment and control of dyslipidemia were estimated overall and compared across race-sex-region strata.

resultsThere were 55% of the participants with dyslipidemia and no racial differences in prevalence. Adjusting for demographic and established stroke risk factors, AAs had a lower prevalence (OR 0.74; 95% CI: 0.66, 0.77) and were less likely to be aware (0.69; 0.61, 0.78), treated (0.77; 0.67, 0.89) and controlled (0.67; 0.58, 0.77) than whites. There was lower control outside of the stroke belt (0.87; 0.76, 0.99).

conclusionRacial, but not geographic, differences in dyslipidemia management may play a role in the excess stroke burden in the Southeast.

Indexed as

Healthcare DisparitiesHealth Knowledge, Attitudes, PracticeAgedAged, 80 and overAwarenessBlack or African AmericanDyslipidemiasHealth Status DisparitiesHumansMaleMiddle AgedPrevalenceRisk FactorsStrokeUnited StatesWhite People

Identifiers

PMID21822024
PMCPMC3171279

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.