ArticleOphthalmology2011
Prevalence and characteristics of choroidal nevi: the multi-ethnic study of atherosclerosis.
Article in Ophthalmology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00041444 (Multi-Ethnic Study of Atherosclerosis-Eye Study), which is not on this map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Multi-Ethnic Study of Atherosclerosis-Eye Study
Who cites it
26 citing papers in PubMed, 60 citations in OpenAlex.
- [Set them free! Better care for more patients with fewer follow-ups].Die Ophthalmologie · 2026Review
- Age distribution and characteristics of choroidal nevi in 35 559 individuals: A nationwide study using optometry fundus photography.Acta ophthalmologica · 2026Article
- Stereo-Vision-Inspired Spectral Disparity Learning for Choroidal Tumor Thickness Prediction.Translational vision science & technology · 2026Article
- Prevalence of choroidal naevi in Germany: a cross-sectional analysis of the BiDirect study.BMC ophthalmology · 2026Observational
- Comparison of MOLES and MelCancers · 2026Article
- Rhegmatogenous Retinal Detachment Associated With a Retinal Tear Overlying a Choroidal Nevus.Case reports in ophthalmological medicine · 2026Article
- Volumes of Choroidal Nevi on Widefield Optical Coherence Tomography Compared to Calculations Based on Ultrasound Measurements.Ophthalmology and therapy · 2026Article
- Longitudinal High-Resolution Imaging of Retinal Sequelae of a Choroidal Nevus.Diagnostics (Basel, Switzerland) · 2025Article
- Case Series: Retinal Pigment Epithelial Detachments Over Choroidal Nevi - What Is the Clinical Significance?Ocular oncology and pathology · 2025Article
- Challenges for Opticians in Evaluating Small Pigmented Choroidal Lesions: Potential Support From the MelAInoma Deep Learning Algorithm.Translational vision science & technology · 2025Article
- Giant Choroidal Nevus-A Case Report.Reports (MDPI) · 2025Article
- Artificial intelligence in the diagnosis of uveal melanoma: advances and applications.Experimental biology and medicine (Maywood, N.J.) · 2025Review
- Single-Shot Ultra-Widefield Polarization-Diversity Optical Coherence Tomography for Assessing Retinal and Choroidal Pathologies.Journal of clinical medicine · 2024Article
- Population-based incidence of intraocular tumours in Olmsted County, Minnesota.The British journal of ophthalmology · 2023Article
- Clinical and Multimodal Imaging Features of Choroidal Nevi in the Korean Population.Journal of clinical medicine · 2022Article
- White Paper on Ophthalmic Imaging for Choroidal Nevus Identification and Transformation into Melanoma.Translational vision science & technology · 2021Article
- Focal aggregates of normal or near normal uveal melanocytes (FANNUMs) in the choroid: a distinct clinical and histopathological entity?Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Article
- Evaluation of 20-MHz high-frequency ultrasonography for the diagnosis of choroidal nevi.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Article
- Detecting Progression of Melanocytic Choroidal Tumors by Sequential Imaging: Is Ultrasonography Necessary?Cancers · 2020Article
- Malignant transformation of choroidal nevus according to race in 3334 consecutive patients.Indian journal of ophthalmology · 2019Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 3 countries.
Funding
Abstract
objectiveTo describe the prevalence of choroidal nevi in 4 racial or ethnic groups (white, black, Hispanic, and Chinese) in the United States.
designCross-sectional study.
participantsParticipants of the second examination of the Multi-Ethnic Study of Atherosclerosis (MESA), involving 6176 persons 44 to 84 years of age without clinical cardiovascular disease at baseline selected from 6 United States communities.
methodsFundus images were taken using a 45° digital camera through dark-adapted pupils and were graded for choroidal nevi using the modified Wisconsin Age-Related Maculopathy Grading System and the Blue Mountains Eye Study protocol.
main outcome measuresChoroidal nevi.
resultsThe overall prevalence of choroidal nevi in the whole cohort was 2.1%, with prevalences higher in whites (4.1%) than blacks (0.7%), Hispanics (1.2%), and Chinese (0.4%; P<0.001 for any differences among groups). The lowest prevalence of choroidal nevi occurred in those 75 to 84 years of age. The nevi were subfoveal in 4% of eyes with nevi and were not associated with a decrease in visual acuity. Characteristics of the nevi (size, shape, location, color, drusen on surface) did not differ among racial or ethnic groups. With the exception of associations with higher C-reactive protein levels (odds ratio [OR] per mg/dl on the logarithmic scale, 1.23; 95% confidence interval [CI], 1.06-1.43; P = 0.01) and lower systolic blood pressure (OR per 10 mmHg, 0.90; 95% CI, 0.82-0.99; P = 0.04), choroidal nevi were not associated with other potential risk factors (e.g., gender, smoking status, alcohol consumption, lipid levels, coagulation factors, or kidney disease).
conclusionsLow prevalences of choroidal nevi were found in the 4 groups participating in the MESA cohort, with whites having higher prevalence than the other racial or ethnic groups. The higher prevalence in whites than in other groups was not explained by any of the factors studied. When choroidal nevi were present, their characteristics did not differ among racial or ethnic groups. FINANCIAL DISCLOSURE(S): The author(s) have no proprietary or commercial interest in any materials discussed in this article.
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