ArticleJournal of neurodevelopmental disorders2011
Turner syndrome and sexual differentiation of the brain: implications for understanding male-biased neurodevelopmental disorders.
Article in Journal of neurodevelopmental disorders, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 42 citations in OpenAlex.
- Giftedness and atypical sexual differentiation: enhanced perceptual functioning through estrogen deficiency instead of androgen excess.Frontiers in endocrinology · 2024Review
- Chromosomal Abnormalities of Interest in Turner Syndrome: An Update.Journal of pediatric genetics · 2023Review
- Chromosomal and gonadal factors regulate microglial sex effects in the aging brain.Brain research bulletin · 2023Review
- Differential Regulation of Mouse Hippocampal Gene Expression Sex Differences by Chromosomal Content and Gonadal Sex.Molecular neurobiology · 2022Article
- The Transcription Factor Shox2 Shapes Neuron Firing Properties and Suppresses Seizures by Regulation of Key Ion Channels in Thalamocortical Neurons.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Less ready for adulthood?-Turner syndrome has an impact on transition readiness.Clinical endocrinology · 2020Article
- Altered Brain Structure in Infants with Turner Syndrome.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Brain Development in School-Age and Adolescent Girls: Effects of Turner Syndrome, Estrogen Therapy, and Genomic Imprinting.Biological psychiatry · 2020Article
- Mental Health of a Large Group of Adults With Disorders of Sex Development in Six European Countries.Psychosomatic medicine · 2019Observational
- A basic understanding of Turner syndrome: Incidence, complications, diagnosis, and treatment.Intractable & rare diseases research · 2018Review
- Obsessive-Compulsive Disorder in a 19-Year-Old Female Adolescent With Turner Syndrome.Journal of clinical medicine research · 2017Article
- Care of girls and women with Turner syndrome: beyond growth and hormones.Endocrine connections · 2017Review
- Assessing prenatal and neonatal gonadal steroid exposure for studies of human development: methodological and theoretical challenges.Frontiers in endocrinology · 2014Article
- Cortical brain morphology in young, estrogen-naive, and adolescent, estrogen-treated girls with Turner syndrome.Cerebral cortex (New York, N.Y. : 1991) · 2013Article
- The patient with Turner syndrome: puberty and medical management concerns.Fertility and sterility · 2012Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Turner syndrome (TS) is one of the most common sex chromosome abnormalities. Affected individuals often show a unique pattern of cognitive strengths and weaknesses and are at increased risk for a number of other neurodevelopmental conditions, many of which are more common in typical males than typical females (e.g., autism and attention-deficit hyperactivity disorder). This phenotype may reflect gonadal steroid deficiency, haploinsufficiency of X chromosome genes, failure to express parentally imprinted genes, and the uncovering of X chromosome mutations. Understanding the contribution of these different mechanisms to outcome has the potential to improve clinical care for individuals with TS and to better our understanding of the differential vulnerability to and expression of neurodevelopmental disorders in males and females. In this paper, we review what is currently known about cognition and brain development in individuals with TS, discuss underlying mechanisms and their relevance to understanding male-biased neurodevelopmental conditions, and suggest directions for future research.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.