ArticleAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2011
A closer look at depression and its relationship to HIV antiretroviral adherence.
Article in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02459678 (ART Readiness in HIV-infected Pregnant Women), which is not on this map. Cited by 82 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
ART Readiness in HIV-infected Pregnant Women: From Formative Qualitative Research to Individual Randomized Trial
Who cites it
82 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- The Global Landscape of the Burden of Depressive Symptoms/Major Depression in Individuals Living With HIV/AIDs and Its Effect on Antiretroviral Medication Adherence: An Umbrella Review.Frontiers in psychiatry · 2022Pooled it
- Prevalence and predictors of medication non-adherence among people living with multimorbidity: a systematic review and meta-analysis.BMJ open · 2021Pooled it
- Psychosocial interventions enhance HIV medication adherence: A systematic review and meta-analysis.Journal of health psychology · 2020Pooled it
- Posttraumatic Stress Disorder and Nonadherence to Treatment in People Living With HIV: A Systematic Review and Meta-analysis.Frontiers in psychiatry · 2020Pooled it
- A Systematic Review and Meta-analysis of Antiretroviral Therapy (ART) Adherence Interventions for Women Living with HIV.AIDS and behavior · 2019Pooled it
- Depression treatment enhances adherence to antiretroviral therapy: a meta-analysis.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2014Pooled it
- The impact of DSM-IV mental disorders on adherence to combination antiretroviral therapy among adult persons living with HIV/AIDS: a systematic review.AIDS and behavior · 2012Pooled it
- Phone-delivered mindfulness training to promote medication adherence and reduce sexual risk behavior among persons living with HIV: Design and methods.Contemporary clinical trials · 2017Trial
- Depression and Oral FTC/TDF Pre-exposure Prophylaxis (PrEP) Among Men and Transgender Women Who Have Sex With Men (MSM/TGW).AIDS and behavior · 2016Trial
- A randomized clinical trial of an intervention to promote resilience in young children of HIV-positive mothers in South Africa.AIDS (London, England) · 2014Trial
- Trial
- A preliminary RCT of CBT-AD for adherence and depression among HIV-positive Latinos on the U.S.-Mexico border: the Nuevo Día study.AIDS and behavior · 2013Trial
- Differentiating Exposure From Consequence: A Longitudinal Examination of Trauma and Posttraumatic Distress in a Public HIV Care Clinic.AIDS and behavior · 2026Article
- Longitudinal analysis of symptoms and healthcare utilization among daily cannabis-using persons living with HIV: impact of co-occurring cocaine use.Journal of cannabis research · 2026Article
- Observational
- Latent Profile Analysis of Cognitive Performance and Depressive Symptoms Among People with HIV.AIDS patient care and STDs · 2024Article
- Substance Use and Depression Impede ART Adherence Among Female Sex Workers Living with HIV in the Dominican Republic.AIDS and behavior · 2023Article
- Psychosocial Interventions by Nurses for Patients with HIV/ AIDS: A Systematic Review.Journal of caring sciences · 2023Review
- Prevalence of depression, syndemic factors and their impact on viral suppression among female sex workers living with HIV in eThekwini, South Africa.BMC women's health · 2023Article
- Development and validation of a novel scale for antiretroviral therapy readiness among pregnant women in urban Zambia with newly diagnosed HIV infection.AIDS research and therapy · 2023Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundDepression consistently predicts nonadherence to human immunodeficiency virus antiretroviral therapy, but which aspects of depression are most influential are unknown. Such knowledge could inform assessments of adherence readiness and the type of depression treatment to utilize. PURPOSE: We examined how depression severity, symptom type, and change over time relate to adherence.
methodsMicroelectronic adherence and self-reported depression data from 1,374 participants across merged studies were examined with cross-sectional and longitudinal analyses. Depression variables included a continuous measure, categorical measure of severity, cognitive and vegetative subscales, and individual symptoms.
resultsAt baseline, mean adherence was 69%, and 25% had mild/moderate and 18% had severe depression. In cross-sectional multivariate analyses, continuous depression, cognitive depressive symptoms, and severe depression were associated with lower adherence. In longitudinal analysis, reductions in both continuous and categorical depression predicted increased adherence.
conclusionsThe relationship between global continuous depression and nonadherence was statistically significant, but relatively weak compared to that of cognitive depressive symptoms and severe depression, which appear to pose strong challenges to adherence and call for the need for early detection and treatment of depression.
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