ReviewNature reviews. Gastroenterology & hepatology2011
New insights into gastrointestinal and hepatic granulomatous disorders.
Review in Nature reviews. Gastroenterology & hepatology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 47 citations in OpenAlex.
- AI digital pathology as a key tool providing in-depth understanding of the progression and regression of MASH and fibrosis in male mouse models.Nature communications · 2026Article
- Granulomatous liver disease in Thailand: a 20-year retrospective clinicoradiopathological analysis.BMJ open gastroenterology · 2025Article
- Granulomatous liver diseases.Hepatology communications · 2024Review
- [Granulomatous disease with liver injury as the main manifestation].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2023Review
- Comorbidity and drug resistance of smear-positive pulmonary tuberculosis patients in the yi autonomous prefecture of China: a cross-sectional study.BMC infectious diseases · 2023Article
- [Hepatic granuloma-A diagnostic challenge].Zeitschrift fur Rheumatologie · 2022Review
- IL-37 alleviates liver granuloma caused by Schistosoma japonicum infection by inducing alternative macrophage activation.Parasites & vectors · 2022Article
- Physiological and pathophysiological functions of NLRP6: pro- and anti-inflammatory roles.Communications biology · 2022Review
- From inflammatory bowel disease to colorectal cancer: what's the role of miRNAs?Cancer cell international · 2022Review
- STAT3 Promotes Schistosome-Induced Liver Injury by Inflammation, Oxidative Stress, Proliferation, and Apoptosis Signal Pathway.Infection and immunity · 2021Article
- Pathogenesis of liver injury in Takayasu arteritis: advanced understanding leads to new horizons.The Journal of international medical research · 2020Article
- Crohn's Disease Patient Infected With Multiple Co-occurring Nontuberculous Mycobacteria.Inflammatory bowel diseases · 2020Article
- Comparative in-silico proteomic analysis discerns potential granuloma proteins of Yersinia pseudotuberculosis.Scientific reports · 2020Article
- NLRP6 Plays an Important Role in Early Hepatic Immunopathology Caused byFrontiers in immunology · 2020Article
- Schistosome infection and its effect on pulmonary circulation.Global cardiology science & practice · 2019Review
- Granulomas in the gastrointestinal tract: deciphering the Pandora's box.Virchows Archiv : an international journal of pathology · 2018Review
- Diagnosis of intestinal tuberculosis using a monoclonal antibody to Mycobacterium tuberculosis.World journal of gastroenterology · 2012Article
- The immunopathology of liver granulomas in primary biliary cirrhosis.Journal of autoimmunity · 2012Article
- Macrophage-related diseases of the gut: a pathologist's perspective.Virchows Archiv : an international journal of pathology · 2012Review
- Distinguishing between Crohn's disease, tuberculosis, and lymphoma: still in murky waters.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology AssociationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Numerous diseases that involve the gastrointestinal tract reveal the presence of granulomas on histological analysis. Granulomatous diseases can be either primary or secondary to environmental factors. Granulomas are dynamic structures composed of organized collections of activated macrophages, including epithelioid and multinucleated giant cells, surrounded by lymphocytes. The formation of granulomas is usually in response to antigenic stimulation and is orchestrated through cytokines, immune cells and host genetics. In this Review, the pathogenesis and etiologies of granulomas of the gastrointestinal tract and liver are discussed, as are the available diagnostic tools to help differentiate their various underlying etiologies. In addition, the role of granulomas in harboring latent tuberculosis is reviewed. The effects of tumor necrosis factor antagonists and interferon-α on the development of granulomas are also discussed.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.