ArticleCancer epidemiology2012
Anthropometric factors, physical activity, and risk of non-Hodgkin's lymphoma in the Women's Health Initiative.
Article in Cancer epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- The relationship between physical activity and lymphoma: a systematic review and meta analysis.BMC cancer · 2020Pooled it
- Medical history, lifestyle, family history, and occupational risk factors for follicular lymphoma: the InterLymph Non-Hodgkin Lymphoma Subtypes Project.Journal of the National Cancer Institute. Monographs · 2014Pooled it
- Genetically determined body mass index is associated with diffuse large B-cell lymphoma in polygenic and Mendelian randomization analyses.International journal of cancer · 2026Article
- Hysterectomy, oophorectomy and risk of non-Hodgkin's lymphoma.International journal of cancer · 2024Article
- Role of epigenetic in cancer biology, in hematologic malignancies and in anticancer therapy.Frontiers in molecular medicine · 2024Review
- Gender Differences in Obesity-Related Cancers.Current obesity reports · 2021Review
- Genetically Determined Height and Risk of Non-hodgkin Lymphoma.Frontiers in oncology · 2019Article
- The Relation of Obesity-Related Hormonal and Cytokine Levels With Multiple Myeloma and Non-Hodgkin Lymphoma.Frontiers in oncology · 2018Review
- Body size in early life and risk of lymphoid malignancies and histological subtypes in adulthood.International journal of cancer · 2016Article
- Non-Hodgkin Lymphoma, Body Mass Index, and Cytokine Polymorphisms: A Pooled Analysis from the InterLymph Consortium.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2015Article
- Electric Blanket Use and Risk of Thyroid Cancer in the Women's Health Initiative Observational Cohort.Women & health · 2015Observational
- A prospective analysis of body size during childhood, adolescence, and adulthood and risk of non-Hodgkin lymphoma.Cancer prevention research (Philadelphia, Pa.) · 2013Article
- Height as an explanatory factor for sex differences in human cancer.Journal of the National Cancer Institute · 2013Article
- The association between early life and adult body mass index and physical activity with risk of non-Hodgkin lymphoma: impact of gender.Annals of epidemiology · 2012Article
- Physical activity and cancer.Current oncology reports · 2012Review
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundIncidence rates of non-Hodgkin's lymphoma (NHL) increased substantially in the United States and worldwide during the latter part of the 20th century, but little is known about its etiology. Obesity is associated with impaired immune function through which it may influence the risk of NHL; other factors reflecting energy homeostasis (height, abdominal adiposity, and physical activity) may also be involved.
methodsWe examined the association of anthropometric factors and physical activity with risk of NHL and its major subtypes in a large cohort of women aged 50-79 years old who were enrolled at 40 clinical centers in the United States between 1993 and 1998. Over a mean follow-up period of 11 years, 1123 cases of NHL were identified among 158,975 women. Cox proportional hazards models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI).
resultsHeight at baseline was positively associated with risk of all NHL and with that of diffuse large B-cell lymphoma (HRs(q4vs.q1) 1.19, 95% CI 1.00-1.43 and 1.43, 95% CI 1.01-2.03, respectively). Measures of obesity and abdominal adiposity at baseline were not associated with risk. Hazard ratios for NHL were increased for women in the highest quartile of weight and body mass index at age 18 (HRs(q4vs.q1) 1.29, 95% CI 1.01-1.65 and 1.27, 95% CI 1.01-1.59, respectively). Some measures of recreational physical activity were modestly associated with increased risk of NHL overall, but there were no clear associations with specific subtypes.
conclusionOur findings regarding anthropometric measures are consistent with those of several previous reports, suggesting that early life influences on growth and immune function may influence the risk of NHL later in life.
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Registered trials
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