ArticleAddiction (Abingdon, England)2012
Factors associated with injection cessation, relapse and initiation in a community-based cohort of injection drug users in Chennai, India.
Article in Addiction (Abingdon, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Risky decision-making in individuals with substance use disorder: A meta-analysis and meta-regression review.Psychopharmacology · 2020Pooled it
- Transition to injecting drug use in Iran: A systematic review of qualitative and quantitative evidence.The International journal on drug policy · 2015Pooled it
- Community health worker and family support for addiction treatment services.Substance abuse treatment, prevention, and policy · 2026Trial
- Correlated outcomes of a pilot intervention for people injecting drugs and their family members in Vietnam.Drug and alcohol dependence · 2014Trial
- Coping strategy as a predictor of illicit drug use among persons who inject drugs.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026Article
- Association between homelessness and PrEP uptake among men who have sex with men: Results from the American Men's Internet Survey, 2017-2021.Social science & medicine (1982) · 2025Article
- Injection cessation and relapse to injection and the associated factors among people who inject drugs in Iran: The Rostam study.Substance abuse treatment, prevention, and policy · 2023Article
- Modelling the impact and cost-effectiveness of non-governmental organizations on HIV and HCV transmission among people who inject drugs in Ukraine.Journal of the International AIDS Society · 2023Article
- Social network predictors of recent and sustained injection drug use cessation: findings from a longitudinal cohort study.Addiction (Abingdon, England) · 2021Article
- Peer influence of injection drug use cessation among dyads in rural eastern Kentucky.The International journal on drug policy · 2020Article
- Frequent Cannabis Use and Cessation of Injection of Opioids, Vancouver, Canada, 2005-2018.American journal of public health · 2020Article
- Evaluating an intervention for family members of people who use drugs in Vietnam.Social science & medicine (1982) · 2020Article
- Opioid use disorder.Nature reviews. Disease primers · 2020Review
- Application of data mining techniques and logistic regression to model drug use transition to injection: a case study in drug use treatment centers in Kermanshah Province, Iran.Substance abuse treatment, prevention, and policy · 2019Article
- Reducing injection intensity is associated with decreased risk for invasive bacterial infection among high-frequency injection drug users.Harm reduction journal · 2019Article
- Predictors of injecting cessation among a cohort of people who inject drugs in Tijuana, Mexico.Drug and alcohol dependence · 2018Article
- Article
- Social-structural factors influencing periods of injection cessation among marginalized youth who inject drugs in Vancouver, Canada: an ethno-epidemiological study.Harm reduction journal · 2017Article
- Drug use generations and patterns of injection drug use: Birth cohort differences among people who inject drugs in Los Angeles and San Francisco, California.Drug and alcohol dependence · 2017Article
- Hepatitis C virus treatment as prevention in people who inject drugs: testing the evidence.Current opinion in infectious diseases · 2015Review
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10 authors at 2 institutions in 2 countries.
Funding
Abstract
aimsTo characterize factors associated with injection cessation, relapse and initiation.
designThe Madras Injection Drug User and AIDS Cohort Study (MIDACS) is a prospective cohort of injection drug users (IDUs) recruited in 2005-06 with semi-annual follow-up to 2009. Discrete-time survival models were used to characterize predictors of time to first injection cessation and relapse.
settingChennai, India.
participantsA total of 855 IDUs who reported injecting in the 6 months prior to baseline and had >1 follow-up visit. MEASUREMENTS: Cessation was defined as the first visit where no injection drug use was reported (prior 6 months) and relapse as the first visit where drug injection (prior 6 months) was reported after first cessation.
findingsAll participants were male; median age was 35 years. Over 3 years, 92.7% reported cessation [incidence rate (IR): 117 per 100 person-years]. Factors associated positively with cessation included daily injection and incarceration and factors associated negatively with cessation included marriage, alcohol and homelessness. Of those who reported cessation, 23.6% relapsed (IR: 19.7 per 100 person-years). Factors associated positively with relapse included any education, injection in the month prior to baseline, sex with a casual partner, non-injection drug use, incarceration and homelessness. Alcohol was associated negatively with relapse. The primary reasons for cessation were medical conditions (37%) and family pressure (22%). The majority initiated with non-injection drugs, transitioning to injection after a median 4 years.
conclusionsInjection drug users in southern India demonstrate a high rate of injection cessation over 3 years, but relapse is not uncommon. Compensatory increases in alcohol use indicate that cessation of injection does not mean cessation of all substance use. Family pressure, concerns about general health, fear of human immunodeficiency virus infection and a history of non-injection drug use are important correlates of cessation.
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